Oh Jung-Hwan, Kang Bong Su, Choi Jay Chol
Department of Neurology, Jeju National University School of Medicine, Jeju, Korea.
Yangpyeong Hospital, Yangpyeong, Korea.
J Epilepsy Res. 2016 Dec 31;6(2):104-106. doi: 10.14581/jer.16020. eCollection 2016 Dec.
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary disease of the cerebral small blood vessels characterized by recurrent ischemic strokes, migraine, and progressive cognitive impairment. In patients with CADASIL, in whom subcortical white matter structures are typically involved, epileptic seizures have been rarely reported as an initial clinical symptom. We describe a patient genetically confirmed as having CADASIL who initially presented with a seizure.
伴有皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病（CADASIL）是一种脑小血管遗传性疾病，其特征为反复缺血性卒中、偏头痛和进行性认知障碍。在CADASIL患者中，皮质下白质结构通常受累，癫痫发作作为初始临床症状鲜有报道。我们描述了一名经基因确诊为CADASIL的患者，其最初表现为癫痫发作。
