State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin 300071, China.
Nanoscale. 2017 Feb 2;9(5):1811-1815. doi: 10.1039/c6nr07879f.
We presented a Janus PEGylated AuNP probe where PEGs and recognition ligands (e.g., 4-aminobenzenethiol, 4-ABT) were asymmetrically functionalized on an AuNP. With this design, the probes showed high colloidal stability, signal robustness, specificity, and sufficient sensitivity in the determination of NO in various complex samples.
我们提出了一种具有双面特性的聚乙二醇化金纳米粒子探针，其中聚乙二醇和识别配体（例如 4-氨基苯硫酚、4-ABT）不对称地功能化在金纳米粒子上。通过这种设计，探针在各种复杂样品中测定 NO 时表现出高胶体稳定性、信号稳健性、特异性和足够的灵敏度。
