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用于化学和生物传感应用的基于金纳米粒子的比色策略。

Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications.

作者信息

Chang Chia-Chen, Chen Chie-Pein, Wu Tzu-Heng, Yang Ching-Hsu, Lin Chii-Wann, Chen Chen-Yu

机构信息

Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu 310, Taiwan.

Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei 104, Taiwan.

出版信息

Nanomaterials (Basel). 2019 Jun 6;9(6):861. doi: 10.3390/nano9060861.

DOI:10.3390/nano9060861
PMID:31174348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6631916/
Abstract

Gold nanoparticles are popularly used in biological and chemical sensors and their applications owing to their fascinating chemical, optical, and catalytic properties. Particularly, the use of gold nanoparticles is widespread in colorimetric assays because of their simple, cost-effective fabrication, and ease of use. More importantly, the gold nanoparticle sensor response is a visual change in color, which allows easy interpretation of results. Therefore, many studies of gold nanoparticle-based colorimetric methods have been reported, and some review articles published over the past years. Most reviews focus exclusively on a single gold nanoparticle-based colorimetric technique for one analyte of interest. In this review, we focus on the current developments in different colorimetric assay designs for the sensing of various chemical and biological samples. We summarize and classify the sensing strategies and mechanism analyses of gold nanoparticle-based detection. Additionally, typical examples of recently developed gold nanoparticle-based colorimetric methods and their applications in the detection of various analytes are presented and discussed comprehensively.

摘要

金纳米颗粒因其迷人的化学、光学和催化特性而广泛应用于生物和化学传感器及其应用领域。特别是，由于其制备简单、成本效益高且易于使用，金纳米颗粒在比色分析中得到了广泛应用。更重要的是，金纳米颗粒传感器的响应是颜色的视觉变化，这使得结果易于解读。因此，已经报道了许多基于金纳米颗粒的比色法研究，并且在过去几年发表了一些综述文章。大多数综述仅专注于针对一种感兴趣的分析物的单一基于金纳米颗粒的比色技术。在本综述中，我们关注用于检测各种化学和生物样品的不同比色分析设计的当前进展。我们总结并分类了基于金纳米颗粒检测的传感策略和机理分析。此外，还全面介绍并讨论了最近开发的基于金纳米颗粒的比色法的典型示例及其在各种分析物检测中的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/f3733e1001c3/nanomaterials-09-00861-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/9c4e0947f491/nanomaterials-09-00861-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/1f45cf886d40/nanomaterials-09-00861-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/7efefae1ce82/nanomaterials-09-00861-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/0c2d11c92959/nanomaterials-09-00861-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/799f08b28176/nanomaterials-09-00861-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/b36c331e2128/nanomaterials-09-00861-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/e9a13b7b8aa3/nanomaterials-09-00861-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/5eb1d18f4b68/nanomaterials-09-00861-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/7a128a81a79b/nanomaterials-09-00861-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/9ab333b6995c/nanomaterials-09-00861-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/318fba5e189b/nanomaterials-09-00861-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/f3733e1001c3/nanomaterials-09-00861-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/9c4e0947f491/nanomaterials-09-00861-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/d6659c01bbca/nanomaterials-09-00861-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/e17ba97ae108/nanomaterials-09-00861-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/1f45cf886d40/nanomaterials-09-00861-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/7efefae1ce82/nanomaterials-09-00861-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/0c2d11c92959/nanomaterials-09-00861-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/799f08b28176/nanomaterials-09-00861-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/b36c331e2128/nanomaterials-09-00861-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/e9a13b7b8aa3/nanomaterials-09-00861-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/5eb1d18f4b68/nanomaterials-09-00861-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/7a128a81a79b/nanomaterials-09-00861-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/9ab333b6995c/nanomaterials-09-00861-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/318fba5e189b/nanomaterials-09-00861-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fafa/6631916/f3733e1001c3/nanomaterials-09-00861-g014.jpg

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