Cellular Photoimmunology Group, Discipline of Infectious Diseases and Immunology, Sydney Medical School at the Charles Perkins Centre, University of Sydney, Australia.
Photochem Photobiol Sci. 2017 Mar 16;16(3):416-425. doi: 10.1039/c6pp00332j.
The Ultraviolet (UV) radiation contained in sunlight is a powerful mutagen and immune suppressant which partly explains why exposure to solar UV is the biggest risk factor for the development of cutaneous tumours. Evidence is building that sunlight may be protective against some internal malignancies. Because patients with these tumours are often vitamin D deficient, this has led some to propose that vitamin D supplementation will be beneficial in the treatment of these cancers. However, the results from already completed trials have been disappointing which has given weight to the argument that there must be something else about sunlight that explains its cancer-protecting properties.
阳光中的紫外线(UV)辐射是一种强大的诱变剂和免疫抑制剂,这在一定程度上解释了为什么暴露在太阳紫外线下是皮肤肿瘤发展的最大风险因素。有证据表明,阳光可能对某些内部恶性肿瘤有保护作用。由于这些肿瘤患者通常缺乏维生素 D,这导致一些人提出维生素 D 补充剂将有益于这些癌症的治疗。然而,已经完成的试验结果令人失望,这使得人们认为,阳光肯定还有其他一些特性可以解释其抗癌特性。