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危重症患者气管切开术应用的循证指南

Evidence-based guidelines for the use of tracheostomy in critically ill patients.

作者信息

Raimondi Néstor, Vial Macarena R, Calleja José, Quintero Agamenón, Cortés Albán, Celis Edgar, Pacheco Clara, Ugarte Sebastián, Añón José M, Hernández Gonzalo, Vidal Erick, Chiappero Guillermo, Ríos Fernando, Castilleja Fernando, Matos Alfredo, Rodriguez Enith, Antoniazzi Paulo, Teles José Mario, Dueñas Carmelo, Sinclair Jorge, Martínez Lorenzo, von der Osten Ingrid, Vergara José, Jiménez Edgar, Arroyo Max, Rodríguez Camilo, Torres Javier, Fernandez-Bussy Sebastián, Nates Joseph L

机构信息

Hospital Municipal Juan A. Fernández, Universidad de Buenos Aires, Buenos Aires, Argentina.

MD Anderson Cancer Center, The University of Texas, Houston, TX, USA; Clínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.

出版信息

J Crit Care. 2017 Apr;38:304-318. doi: 10.1016/j.jcrc.2016.10.009. Epub 2016 Oct 20.

Abstract

OBJECTIVES

To provide evidence-based guidelines for tracheostomy in critically ill adult patients and identify areas needing further research.

METHODS

A taskforce composed of representatives of 10 member countries of the Pan-American and Iberic Federation of Societies of Critical and Intensive Therapy Medicine and of the Latin American Critical Care Trial Investigators Network developed recommendations based on the Grading of Recommendations Assessment, Development and Evaluation system.

RESULTS

The group identified 23 relevant questions among 87 issues that were initially identified. In the initial search, 333 relevant publications were identified, of which 226 publications were chosen. The taskforce generated a total of 19 recommendations, 10 positive (1B, 3; 2C, 3; 2D, 4) and 9 negative (1B, 8; 2C, 1). A recommendation was not possible in 6 questions.

CONCLUSIONS

Percutaneous techniques are associated with a lower risk of infections compared with surgical tracheostomy. Early tracheostomy only seems to reduce the duration of ventilator use but not the incidence of pneumonia, the length of stay, or the long-term mortality rate. The evidence does not support the use of routine bronchoscopy guidance or laryngeal masks during the procedure. Finally, proper prior training is as important or even a more significant factor in reducing complications than the technique used.

摘要

目的

为危重症成年患者气管切开术提供循证指南,并确定需要进一步研究的领域。

方法

由泛美和伊比利亚危重症与重症治疗医学会10个成员国的代表以及拉丁美洲重症监护试验研究者网络组成的特别工作组,根据推荐分级评估、制定和评价系统制定了相关建议。

结果

该小组在最初确定的87个问题中识别出23个相关问题。在初步检索中,识别出333篇相关出版物,从中选取了226篇。特别工作组共提出了19条建议,其中10条为肯定性建议(1B级,3条;2C级,3条;2D级,4条),9条为否定性建议(1B级,8条;2C级,1条)。6个问题无法给出建议。

结论

与外科气管切开术相比,经皮技术感染风险较低。早期气管切开术似乎仅能缩短机械通气时间,但不能降低肺炎发生率、住院时间或长期死亡率。现有证据不支持在手术过程中使用常规支气管镜引导或喉罩。最后,与所采用的技术相比,适当的术前培训对于减少并发症同样重要甚至更为关键。

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