心脏X综合征与冠状动脉疾病患者的心室晚电位比较。

Ventricular late potential in cardiac syndrome X compared to coronary artery disease.

作者信息

Lutfi Mohamed Faisal

机构信息

Department of Physiology, Faculty of Medicine and Health Sciences, Al-Neelain University, Khartoum, Sudan.

出版信息

BMC Cardiovasc Disord. 2017 Jan 19;17(1):35. doi: 10.1186/s12872-017-0469-6.

DOI:10.1186/s12872-017-0469-6

PMID:28103808

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5244555/

Abstract

BACKGROUND

Although ventricular late potential (VLP) was extensively studied in risk stratification of myocardial infarction (MI) patients, comparable researches evaluating presence of VLP in MI-free coronary artery disease (CAD) and cardiac syndrome X (CSX) subjects are scarce. This study aimed to compare presence of VLP between CSX and CAD patients.

METHODS

Signal average ECG (SAECG) was performed to 49 patients with a history of typical cardiac pain before undergoing diagnostic coronary angiography (DCA) in Al-Shaab cardiac center, Khartoum, Sudan. QRS duration, duration of the terminal part of the QRS complex with amplitude less than 40 microvolts (LAS40) and the root mean square voltage of the terminal 40 milliseconds (RMS40) of the filtered QRS complex were identified for each patient. Presence of two or more of QRS duration > 120 ms, RMS40 > 38 ms and LAS40 < 20 μV was considered indicative of VLP. Associations between VLP and patients grouped according to DCA results were assessed using appropriate statistical tests.

RESULTS

VLP was present in 11.11% (3.63%-24.66%) and 15.38% (2.66%-42.23%) of patients with CAD and CSX respectively. Presence of VLP was comparable in patients with CAD and CSX (OR = 0.69, 95% CI = 0.11-6.05, P = 0.692), even after controlling for the possible variations in gender, age, body mass index (BMI), hypertension and diabetes mellitus in the studied groups.

CONCLUSION

Presence of VLP is comparable among CSX and CAD patients.

摘要

背景

尽管心室晚电位（VLP）在心肌梗死（MI）患者的危险分层中得到了广泛研究，但评估无MI的冠状动脉疾病（CAD）和心脏综合征X（CSX）患者中VLP存在情况的类似研究却很少。本研究旨在比较CSX和CAD患者中VLP的存在情况。

方法

在苏丹喀土穆的沙巴布心脏中心，对49例有典型心前区疼痛病史的患者在进行诊断性冠状动脉造影（DCA）之前进行信号平均心电图（SAECG）检查。确定每位患者的QRS波时限、QRS波群终末部分振幅小于40微伏（LAS40）的时限以及滤波后QRS波群终末40毫秒的均方根电压（RMS40）。QRS波时限>120毫秒、RMS40>38毫秒和LAS40<20微伏中的两项或更多项被认为提示VLP。使用适当的统计检验评估VLP与根据DCA结果分组的患者之间的关联。

结果

CAD患者和CSX患者中VLP的存在率分别为11.11%（3.63%-24.66%）和15.38%（2.66%-42.23%）。CAD患者和CSX患者中VLP的存在情况相当（OR = 0.69，95%CI = 0.11-6.05，P = 0.692），即使在控制了研究组中性别、年龄、体重指数（BMI）、高血压和糖尿病的可能差异之后。