Dorow Marie, Löbner Margrit, Stein Janine, Konnopka Alexander, Meisel Hans J, Günther Lutz, Meixensberger Jürgen, Stengler Katarina, König Hans-Helmut, Riedel-Heller Steffi G
Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany.
Department of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
PLoS One. 2017 Jan 20;12(1):e0170303. doi: 10.1371/journal.pone.0170303. eCollection 2017.
Pain relief has been shown to be the most frequently reported goal by patients undergoing lumbar disc surgery. There is a lack of systematic research investigating the course of postsurgical pain intensity and factors associated with postsurgical pain. This systematic review focuses on pain, the most prevalent symptom of a herniated disc as the primary outcome parameter. The aims of this review were (1) to examine how pain intensity changes over time in patients undergoing surgery for a lumbar herniated disc and (2) to identify socio-demographic, medical, occupational and psychological factors associated with pain intensity.
Selection criteria were developed and search terms defined. The initial literature search was conducted in April 2015 and involved the following databases: Web of Science, Pubmed, PsycInfo and Pubpsych. The course of pain intensity and associated factors were analysed over the short-term (≤ 3 months after surgery), medium-term (> 3 months and < 12 months after surgery) and long-term (≥ 12 months after surgery).
From 371 abstracts, 85 full-text articles were reviewed, of which 21 studies were included. Visual analogue scales indicated that surgery helped the majority of patients experience significantly less pain. Recovery from disc surgery mainly occurred within the short-term period and later changes of pain intensity were minor. Postsurgical back and leg pain was predominantly associated with depression and disability. Preliminary positive evidence was found for somatization and mental well-being.
Patients scheduled for lumbar disc surgery should be selected carefully and need to be treated in a multimodal setting including psychological support.
疼痛缓解已被证明是接受腰椎间盘手术患者最常报告的目标。目前缺乏对术后疼痛强度变化过程以及与术后疼痛相关因素的系统性研究。本系统评价聚焦于疼痛,这是椎间盘突出最普遍的症状,并将其作为主要结局参数。本评价的目的是:(1)研究接受腰椎间盘突出症手术患者的疼痛强度如何随时间变化;(2)确定与疼痛强度相关的社会人口学、医学、职业和心理因素。
制定了选择标准并定义了检索词。2015年4月进行了初步文献检索,涉及以下数据库:科学网、PubMed、PsycInfo和Pubpsych。分析了短期(术后≤3个月)、中期(术后>3个月且<12个月)和长期(术后≥12个月)的疼痛强度变化过程及相关因素。
从371篇摘要中筛选出85篇全文进行评审,其中纳入了21项研究。视觉模拟量表显示,手术帮助大多数患者显著减轻了疼痛。椎间盘手术的恢复主要发生在短期内,术后疼痛强度的后期变化较小。术后腰腿痛主要与抑郁和残疾有关。在躯体化和心理健康方面发现了初步的阳性证据。
计划进行腰椎间盘手术的患者应仔细挑选,并需要在包括心理支持在内的多模式环境中接受治疗。