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头孢特仑新戊酯在儿科领域的临床研究

[Clinical study on cefteram pivoxil in pediatric field].

作者信息

Fujita M, Kanda T, Nagayama E

机构信息

Department of Pediatrics, Kanto Teishin Hospital.

出版信息

Jpn J Antibiot. 1989 Aug;42(8):1845-8.

PMID:2810747
Abstract

Cefteram pivoxil (CFTM-PI, T-2588) was administered to pediatric patients with acute infectious diseases, and a summary of the results obtained are as follows. 1. Pharmacokinetic parameters determined in 1 patient appears to be comparable to those of adults. 2. Clinical efficacy was studied on 16 children with acute urinary tract infections, acute upper respiratory infections, acute sinusitis, acute otitis media and acute cervical lymphadenitis. Responses to the treatment were excellent in 7 (43.8%) and good in 9 (56.3%). 3. No adverse reactions were noted in this study.

摘要

头孢特仑新戊酯(CFTM-PI,T-2588)用于患有急性传染病的儿科患者,所得结果总结如下。1. 在1例患者中测定的药代动力学参数似乎与成人相当。2. 对16名患有急性尿路感染、急性上呼吸道感染、急性鼻窦炎、急性中耳炎和急性颈淋巴结炎的儿童进行了临床疗效研究。治疗反应优者7例(43.8%),良者9例(56.3%)。3. 本研究中未观察到不良反应。

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