Satoh Yukitoshi, Ishikawa Yuichi
Department of Thoracic Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0374, Japan.
Department of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo 135-8550, Japan.
Int J Surg Case Rep. 2017;31:58-60. doi: 10.1016/j.ijscr.2017.01.002. Epub 2017 Jan 7.
Primary pulmonary meningiomas (PPMs) are very rare neoplasms, and we reported the first multiple case of PPMs in 1998. Usually, PPMs are slow-growing tumors with a good prognosis. Herein, we reported a rare multiple case of PPMs with an extremely long clinical course.
An 84-year-old Japanese woman with a history of multiple PPMs histologically confirmed as having a right-sided slowly growing lung nodule for 20 years. In 2010, we also reported the additional clinical course in the initial case 10 years after surgery implying a benign biological nature. Subsequent to that report, new lesions appeared in the bilateral lung fields with quite a slow growth rate. She was asymptomatic, and no tumor was observed in the cranial cavity during the course of her disease.
This case illustrates rare multiple PPMs and highlights their biological behavior with very slow progression from a most likely benign tumor over a 20-year period.
原发性肺脑膜瘤（PPM）是非常罕见的肿瘤，我们在1998年报道了首例多发型PPM。通常，PPM是生长缓慢的肿瘤，预后良好。在此，我们报道了一例罕见的多发型PPM，其临床病程极长。
一名84岁的日本女性，有多发PPM病史，经组织学证实右侧肺有一个缓慢生长的结节已20年。2010年，我们还报道了该首例病例术后10年的后续临床病程，提示其生物学特性为良性。在该报道之后，双肺野出现了新病灶，生长速度相当缓慢。她没有症状，在病程中未发现颅内有肿瘤。
本病例展示了罕见的多发型PPM，并突出了其生物学行为，即从一个极有可能为良性的肿瘤在20年的时间里进展非常缓慢。
