Lockett L, Chiang V, Scully N
Department of Anatomic Pathology, Straub Clinic & Hospital, Honolulu, HI 96813, USA.
Am J Surg Pathol. 1997 Apr;21(4):453-60. doi: 10.1097/00000478-199704000-00012.
Ten cases of benign primary pulmonary meningioma have been reported in the English literature. We describe herein an additional case of a benign meningioma arising in the lung showing comparable histologic features of sheets and whorls of epithelioid and meningothelial cells with numerous psammoma bodies. Immunohistochemistry showed that the tumor expressed vimentin and epithelial membrane antigen and was negative for keratin, CD34, glial fibrillary acidic protein, CAM 5.2 and S-100, in keeping with previously reported findings. Our review of the literature reveals similar clinical presentations and follow-up behavior and, where reported, similar electron microscopic and immunostaining features.
英文文献中已报道了10例原发性肺良性脑膜瘤病例。我们在此描述另外1例发生于肺部的良性脑膜瘤病例，其组织学特征为上皮样细胞和脑膜内皮细胞呈片状及漩涡状排列，伴有大量砂粒体，与已报道的病例相似。免疫组化显示，该肿瘤表达波形蛋白和上皮膜抗原，而角蛋白、CD34、胶质纤维酸性蛋白、CAM 5.2和S-100均为阴性，这与先前报道的结果一致。我们对文献的回顾显示，这些病例具有相似的临床表现和随访情况，在有报道的情况下，其电镜和免疫染色特征也相似。
