Iba T, Kidokoro A, Yagi Y, Sumi Y, Kawahata S, Horiuchi H, Ishi K
Nihon Shokakibyo Gakkai Zasshi. 1989 Jul;86(7):1455-9.
The reticuloendothelial system is important as one of the self defense mechanisms. We performed two investigations to confirm the reliability of the lipid emulsion test for determining the reticuloendothelial system function. 1) The lipid emulsion serum clearance was contrasted with the counts of lipid emulsions phagocytosed by Kupffer cells in liver. 2) Lipid emulsion clearance was contrasted with the hepatic uptake rate of 99mTc-phytate. The result demonstrated a positive correlation among lipid emulsion clearance, the counts of lipid emulsions phagocytosed by Kupffer cells and the hepatic uptake rate of 99mTc-phytate. These results confirm that the lipid emulsion test is sufficient to reflect Reticuloendothelial system function.
网状内皮系统作为一种自我防御机制很重要。我们进行了两项研究以证实脂质乳剂试验用于测定网状内皮系统功能的可靠性。1)对比脂质乳剂的血清清除率与肝脏中库普弗细胞吞噬的脂质乳剂数量。2)对比脂质乳剂清除率与99mTc-植酸盐的肝脏摄取率。结果表明脂质乳剂清除率、库普弗细胞吞噬的脂质乳剂数量以及99mTc-植酸盐的肝脏摄取率之间呈正相关。这些结果证实脂质乳剂试验足以反映网状内皮系统功能。