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[睡眠脑电图基线研究——日变化与个体差异]

[Baseline study of sleep electroencephalography--daily variation and individual variation].

作者信息

Kimura K, Kawada T, Takeuchi K, Ogawa M, Aoki S, Suzuki S

出版信息

Nihon Eiseigaku Zasshi. 1989 Jun;44(2):567-78. doi: 10.1265/jjh.44.567.

DOI:10.1265/jjh.44.567
PMID:2810858
Abstract

The aims of the present study were to observe the daily habituation to night sleep in a laboratory environment and to make clear the daily and individual sleep variations by using polygraph parameters, including electroencephalography (EEG). Sleep EEG records were obtained from a subject who slept ten successive nights, and from six subjects who each slept one night in the laboratory. The parameters used were as follows: sleep stage %, sleep latency (SL), REM latency (RL), number of stage shifts, subjective sleep, integral EMG, and slope (a) and intersect (b) of a regression equation used to estimate the sleep depth against sleep time. Stage WAKE and SL, slope (a), intersect (b) and the mean depth of sleep were found to become stable from the fifth night. Stage MT, the number of stage shifts, and integral EMG increased significantly from the fifth night and later, showing p less than 0.01, p less than 0.01, and p less than 0.05, respectively. Judging from these findings, the sleep habituation of the subject in the laboratory was completed within the first four nights. Coefficients of variation of sleep stage 2 and stage REM of the ten-nights' EEG were the lowest among all the sleep parameters examined. Almost all the parameters of day-to-day sleep of the subject who slept for ten successive nights in the laboratory showed smaller variations than those of the other six subjects. It may be concluded that the mist effect on sleep could be assessed more precisely by using an individual repeatedly than by using a group of subjects.

摘要

本研究的目的是观察在实验室环境中对夜间睡眠的日常适应性,并通过使用包括脑电图(EEG)在内的多导生理参数来明确每日和个体的睡眠变化。从一名连续睡了十个晚上的受试者以及六名在实验室各睡了一晚的受试者那里获取了睡眠EEG记录。所使用的参数如下:睡眠阶段百分比、睡眠潜伏期(SL)、快速眼动潜伏期(RL)、阶段转换次数、主观睡眠、积分肌电图以及用于估计睡眠深度与睡眠时间关系的回归方程的斜率(a)和截距(b)。发现从第五晚开始,清醒阶段和SL、斜率(a)、截距(b)以及平均睡眠深度变得稳定。从第五晚及之后,中间过渡阶段、阶段转换次数和积分肌电图显著增加,分别显示p值小于0.01、p值小于0.01和p值小于0.05。从这些发现来看,该受试者在实验室中的睡眠适应性在前四个晚上内完成。在所有检查的睡眠参数中,十晚EEG的睡眠第二阶段和快速眼动阶段的变异系数最低。在实验室连续睡了十个晚上的受试者的几乎所有日常睡眠参数的变化都比其他六名受试者的小。可以得出结论,与使用一组受试者相比,通过反复使用个体来评估薄雾对睡眠的影响可能会更精确。

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