变应原依赖性氧化剂的形成需要嘌呤受体激活ADAM 10和凝血酶原。 - Suppr

Suppr

超能文献

Allergen-dependent oxidant formation requires purinoceptor activation of ADAM 10 and prothrombin.

作者信息

Chen Jie, Zhang Jihui, Tachie-Menson Theresa, Shukla Neha, Garrod David R, Robinson Clive

机构信息

Institute for Infection and Immunity, St George's, University of London, London, United Kingdom.

Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.

出版信息

J Allergy Clin Immunol. 2017 Jun;139(6):2023-2026.e9. doi: 10.1016/j.jaci.2016.12.954. Epub 2017 Jan 19.

DOI:10.1016/j.jaci.2016.12.954

PMID:28111309

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5457034/

Abstract

摘要

相似文献

Allergen-dependent oxidant formation requires purinoceptor activation of ADAM 10 and prothrombin.变应原依赖性氧化剂的形成需要嘌呤受体激活ADAM 10和凝血酶原。

J Allergy Clin Immunol. 2017 Jun;139(6):2023-2026.e9. doi: 10.1016/j.jaci.2016.12.954. Epub 2017 Jan 19.

Pathways of airway oxidant formation by house dust mite allergens and viral RNA converge through myosin motors, pannexons and Toll-like receptor 4.屋尘螨变应原和病毒 RNA 通过肌球蛋白马达、连接蛋白和 Toll 样受体 4 形成气道氧化剂的途径汇聚。

Immun Inflamm Dis. 2018 Jun;6(2):276-296. doi: 10.1002/iid3.216. Epub 2018 Mar 15.

Editorial Comment.编辑评论。

J Urol. 2017 Jun;197(6):1572. doi: 10.1016/j.juro.2017.01.082. Epub 2017 Feb 22.

Increased plasma reactive oxidant levels and their relationship to blood cells, total IgE, and allergen-specific IgE levels in asthmatic children.哮喘儿童血浆活性氧化剂水平升高及其与血细胞、总IgE和过敏原特异性IgE水平的关系。

J Asthma. 2009 Sep;46(7):687-91. doi: 10.1080/02770900903056179.

Meprin β induces activities of A disintegrin and metalloproteinases 9, 10, and 17 by specific prodomain cleavage.Meprin β 通过特异性前导序列切割诱导解整合素金属蛋白酶 9、10 和 17 的活性。

FASEB J. 2019 Nov;33(11):11925-11940. doi: 10.1096/fj.201801371R. Epub 2019 Aug 9.

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of murine liver tissue homeostasis.解整合素金属蛋白酶10（ADAM10）是小鼠肝脏组织稳态的核心调节因子。

Oncotarget. 2016 Apr 5;7(14):17431-41. doi: 10.18632/oncotarget.7836.

ADAM10 sheddase activation is controlled by cell membrane asymmetry.ADAM10 脱落酶的激活受细胞膜不对称性的控制。

J Mol Cell Biol. 2019 Dec 23;11(11):979-993. doi: 10.1093/jmcb/mjz008.

Pseudomonas aeruginosa ExlA and Serratia marcescens ShlA trigger cadherin cleavage by promoting calcium influx and ADAM10 activation.铜绿假单胞菌ExlA和粘质沙雷氏菌ShlA通过促进钙内流和ADAM10激活触发钙粘蛋白裂解。

PLoS Pathog. 2017 Aug 23;13(8):e1006579. doi: 10.1371/journal.ppat.1006579. eCollection 2017 Aug.

Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17.胰岛素样生长因子-1 通过调节 ADAM10 和 ADAM17，以依赖于脂生成的上皮-间充质转化的方式，以细胞类型依赖性方式激活不同的 PI3K 的 p110 催化亚基。

Mol Cell Biochem. 2018 Feb;439(1-2):199-211. doi: 10.1007/s11010-017-3148-0. Epub 2017 Aug 17.

Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10.α-分泌酶ADAM10介导的蛋白水解调控的结构基础

Cell. 2017 Dec 14;171(7):1638-1648.e7. doi: 10.1016/j.cell.2017.11.014. Epub 2017 Dec 7.

引用本文的文献

ATP functions as a primary alarmin in allergen-induced type 2 immunity.ATP 作为变应原诱导的 2 型免疫中的主要警报素发挥作用。

Am J Physiol Cell Physiol. 2023 Nov 1;325(5):C1369-C1386. doi: 10.1152/ajpcell.00370.2023. Epub 2023 Oct 16.

Protease allergens as initiators-regulators of allergic inflammation.蛋白酶过敏原作为过敏炎症的启动子-调节剂。

Allergy. 2023 May;78(5):1148-1168. doi: 10.1111/all.15678. Epub 2023 Feb 26.

Targeting an Initiator Allergen Provides Durable and Expansive Protection against House Dust Mite Allergy.针对引发性过敏原可提供针对屋尘螨过敏的持久且广泛的保护。

ACS Pharmacol Transl Sci. 2022 Aug 12;5(9):735-751. doi: 10.1021/acsptsci.2c00022. eCollection 2022 Sep 9.

Insights Into Mucosal Innate Immune Responses in House Dust Mite-Mediated Allergic Asthma.深入了解屋尘螨介导的变应性哮喘中的黏膜先天免疫反应。

Front Immunol. 2020 Dec 7;11:534501. doi: 10.3389/fimmu.2020.534501. eCollection 2020.

Potential Role of Cellular Senescence in Asthma.细胞衰老在哮喘中的潜在作用。

Front Cell Dev Biol. 2020 Feb 11;8:59. doi: 10.3389/fcell.2020.00059. eCollection 2020.

Cellular and Molecular Events in the Airway Epithelium Defining the Interaction Between House Dust Mite Group 1 Allergens and Innate Defences.气道上皮细胞和分子事件定义了屋尘螨 1 类变应原与先天防御之间的相互作用。

Int J Mol Sci. 2018 Nov 10;19(11):3549. doi: 10.3390/ijms19113549.

Allergen Delivery Inhibitors: Characterisation of Potent and Selective Inhibitors of Der p 1 and Their Attenuation of Airway Responses to House Dust Mite Allergens.变应原传递抑制剂：Der p 1 强效和选择性抑制剂的特性及其对屋尘螨变应原引起的气道反应的抑制作用。

Int J Mol Sci. 2018 Oct 15;19(10):3166. doi: 10.3390/ijms19103166.

Allergen Delivery Inhibitors: A Rationale for Targeting Sentinel Innate Immune Signaling of Group 1 House Dust Mite Allergens through Structure-Based Protease Inhibitor Design.变应原递呈抑制剂：通过基于结构的蛋白酶抑制剂设计靶向 1 组屋尘螨变应原哨兵先天免疫信号的理由。

Mol Pharmacol. 2018 Sep;94(3):1007-1030. doi: 10.1124/mol.118.112730. Epub 2018 Jul 5.

Immun Inflamm Dis. 2018 Jun;6(2):276-296. doi: 10.1002/iid3.216. Epub 2018 Mar 15.

本文引用的文献

Innate generation of thrombin and intracellular oxidants in airway epithelium by allergen Der p 1.变应原Der p 1在气道上皮细胞中引发凝血酶和细胞内氧化剂的天然生成。

J Allergy Clin Immunol. 2016 Oct;138(4):1224-1227. doi: 10.1016/j.jaci.2016.05.006. Epub 2016 May 24.

ADAM10 mediates the house dust mite-induced release of chemokine ligand CCL20 by airway epithelium.ADAM10 介导屋尘螨诱导的气道上皮细胞趋化因子配体 CCL20 的释放。

Allergy. 2015 Dec;70(12):1545-52. doi: 10.1111/all.12730. Epub 2015 Sep 11.

Increased B Cell ADAM10 in Allergic Patients and Th2 Prone Mice.过敏性患者和Th2倾向小鼠中B细胞ADAM10增加。

PLoS One. 2015 May 1;10(5):e0124331. doi: 10.1371/journal.pone.0124331. eCollection 2015.

The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma.强效、选择性和可逆性屋尘螨肽酶变应原Der p 1抑制剂的发现：治疗过敏性哮喘的创新方法

J Med Chem. 2014 Nov 26;57(22):9447-62. doi: 10.1021/jm501102h. Epub 2014 Nov 17.

Biased signaling of protease-activated receptors.蛋白酶激活受体的偏向性信号传导

Front Endocrinol (Lausanne). 2014 May 13;5:67. doi: 10.3389/fendo.2014.00067. eCollection 2014.

Thrombin promotes matrix metalloproteinase-13 expression through the PKCδ c-Src/EGFR/PI3K/Akt/AP-1 signaling pathway in human chondrocytes.凝血酶通过人软骨细胞中的蛋白激酶 Cδ(c-Src)/表皮生长因子受体(EGFR)/PI3K/Akt/AP-1 信号通路促进基质金属蛋白酶-13 的表达。

Mediators Inflamm. 2013;2013:326041. doi: 10.1155/2013/326041. Epub 2013 Dec 9.

Proteinase-activated receptors (PARs) - focus on receptor-receptor-interactions and their physiological and pathophysiological impact.蛋白酶激活受体（PARs）——聚焦于受体-受体相互作用及其生理和病理生理学影响。

Cell Commun Signal. 2013 Nov 11;11:86. doi: 10.1186/1478-811X-11-86.

Dose-dependent differential effects of thrombin in allergic bronchial asthma.在变应性支气管哮喘中，凝血酶呈现出剂量依赖性的差异效应。

J Thromb Haemost. 2013 Oct;11(10):1903-15. doi: 10.1111/jth.12392.

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.基质金属蛋白酶 13 通过激活 TNF 调节炎症性疾病中的肠道上皮屏障完整性。

EMBO Mol Med. 2013 Jul;5(7):1000-16. doi: 10.1002/emmm.201202100. Epub 2013 May 30.

Nonhuman targets in allergic lung conditions.过敏性肺部疾病中的非人类靶标。

Future Med Chem. 2013 Feb;5(2):147-61. doi: 10.4155/fmc.12.204.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验