Somnay Yash R, Schneider David, Mazeh Haggi
Section of Endocrine Surgery, Department of Surgery, University of Wisconsin, K3/704 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792, USA (YS, DS, HM).
Atlas Genet Cytogenet Oncol Haematol. 2013 Apr;17(4):291-296. doi: 10.4267/2042/48876.
Medullary thyroid cancers (MTC) are rare neuroendocrine tumors arising from the parafollicular C-cells of the thyroid. In this review, we provide a general overview of the classification, pathology, and clinical management of MTC. In the latter half, we survey the underlying genetic framework of MTC and its potential implications within a diagnostic and therapeutic context.
甲状腺髓样癌（MTC）是一种罕见的神经内分泌肿瘤，起源于甲状腺的滤泡旁C细胞。在本综述中，我们概述了MTC的分类、病理学及临床管理。在后半部分，我们探究了MTC的潜在遗传框架及其在诊断和治疗背景下的潜在意义。
