Sherf Sahar, Martinez Dorothy
University of California, Los Angeles.
Acta Biomed. 2016 Jan 16;87(3):310-313.
Leydig cell tumors of the ovary account for less than 0.1% of all ovarian tumors (1). We present two cases in which patients had markedly elevated serum testosterone levels and frank hirsutism. Both cases revealed right ovarian Leydig cell tumors upon oophorectomy with post-surgical resolution of hypertestosteronemia. While rare and difficult to diagnose, androgen secreting tumors should be suspected in women with hyperandrogenism and hirsutism, especially in the postmenopausal population.
卵巢间质细胞瘤占所有卵巢肿瘤的比例不到0.1%（1）。我们报告两例患者血清睾酮水平显著升高且伴有明显多毛症的病例。两例患者经卵巢切除术后均发现右侧卵巢间质细胞瘤，术后高睾酮血症得以缓解。虽然雄激素分泌性肿瘤罕见且难以诊断，但对于有高雄激素血症和多毛症的女性，尤其是绝经后女性，应怀疑此类肿瘤。
