Jaimovich G, Martinez Rolon J, Baldomero H, Rivas M, Hanesman I, Bouzas L, Bonfim C, Palma J, Kardus-Urueta A, Ubidia D, Bujan-Boza W, Gonzalez-Ramella O, Ruiz-Argüelles G, Gomez-Almaguer D, Espino G, Fanilla E, Gonzalez D, Carrasco A, Galeano S, Borelli G, Hernandez-Gimenez M, Pasquini M, Kodera Y, Gratwohl A, Gratwohl M, Nuñez J, Szer J, Gale R P, Niederwieser D, Seber A
Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina.
FUNDALEU, Buenos Aires, Argentina.
Bone Marrow Transplant. 2017 May;52(5):671-677. doi: 10.1038/bmt.2016.361. Epub 2017 Jan 23.
Haematopoietic cell transplant activity in the 28 countries comprising Latin America is poorly defined. We conducted a voluntary survey of members of the Latin American Bone Marrow Transplantation Group regarding transplant activity 2009-2012. Collated responses were compared with data of transplant rates from the Worldwide Network for Blood and Marrow Transplantation for other geographic regions. Several socio-economic variables were analysed to determine correlations with transplant rates. In total, 94 teams from 12 countries reported 11 519 transplants including 7033 autotransplants and 4486 allotransplants. Annual activity increased from 2517 transplants in 2009 to 3263 in 2012, a 30% increase. Median transplants rate (transplant per million inhabitants) in 2012 was 64 (autotransplants, median 40; allotransplants, median 24). This rate is substantially lower than that in North America and European regions (482 and 378) but higher than that in the Eastern Mediterranean and Asia Pacific regions (30 and 45). However, the Latin America transplant rate is 5-8-fold lower than that in America and Europe, suggesting a need to increase transplant availability. Transplant team density in Latin America (teams per million population; 1.8) is 3-4-fold lower than that in North America (6.2) or Europe (7.6). Within Latin America, there is substantial diversity in transplant rates by country partially explained by diverse socio-economic variables including per capita gross national income, health expenditure and physician density. These data should help inform future health-care policy in Latin America.
拉丁美洲28个国家的造血细胞移植活动情况界定不清。我们针对拉丁美洲骨髓移植小组的成员开展了一项关于2009 - 2012年移植活动的自愿调查。将整理后的回复与全球血液和骨髓移植网络中其他地理区域的移植率数据进行了比较。分析了若干社会经济变量以确定与移植率的相关性。共有来自12个国家的94个团队报告了11519例移植手术,其中包括7033例自体移植和4486例异体移植。年移植活动量从2009年的2517例增加到2012年的3263例,增长了30%。2012年的移植率中位数(每百万居民中的移植例数)为64(自体移植中位数为40;异体移植中位数为24)。这一比率显著低于北美和欧洲地区(分别为482和378),但高于东地中海和亚太地区(分别为30和45)。然而,拉丁美洲的移植率比美洲和欧洲低5至8倍,这表明需要提高移植可及性。拉丁美洲的移植团队密度(每百万人口中的团队数;1.8)比北美(6.2)或欧洲(7.6)低3至4倍。在拉丁美洲内部,各国的移植率存在很大差异,部分原因可由多种社会经济变量解释,包括人均国民总收入、卫生支出和医生密度。这些数据应有助于为拉丁美洲未来的医疗政策提供参考。