Geiker N R W, Horn J, Astrup A
Clinical Nutrition Research Unit, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark.
Department of Plastic Surgery, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark.
Clin Obes. 2017 Apr;7(2):98-104. doi: 10.1111/cob.12175. Epub 2017 Jan 23.
Among women with hypertrophic breasts, the clear majority are overweight or obese. Owing to increased risk of complications, women with a body mass index (BMI) above 25 kg m are precluded from reduction mammaplasty. The primary aim was to investigate if intensive weight loss could ready women with overweight for breast reduction surgery. Six women, all overweight [BMI 30.9 {28.5; 35.8} kg m ] with symptomatic hypertrophy of the breast, were included a 12-week weight loss program. All women desired reduction mammaplasty and were motivated for preoperational weight loss. The first 8 weeks consisted of a formula-based diet supplying 800 kcal daily, in the subsequent 4 weeks regular foods were reintroduced increasing the intake to 1200 kcal daily. Five women completed the trial, and achieved a median (range) weight loss of 10.2 (6.5; 19) kg. Initial breast volume was 1100-2500 mL per breast, this was reduced by 300 (200; 500) mL after the intervention; equivalent to approximately 19%. Waist, hip, upper arm and thorax circumference were significantly reduced following weight loss. At end of study, all the women still suffered from symptomatic breast hypertrophy to substantiate reduction mammaplasty. Surgeries were performed 2 months thereafter. A 12-week intensive preoperative weight loss program enabled women with obesity for breast reduction surgery. Breast size was reduced proportionally more than total weight loss among women with hypertrophy.
在乳房肥大的女性中,绝大多数超重或肥胖。由于并发症风险增加,体重指数(BMI)高于25 kg/m²的女性不能进行乳房缩小整形术。主要目的是研究强化减肥是否能使超重女性为乳房缩小手术做好准备。六名超重[BMI 30.9{28.5; 35.8}kg/m²]且有症状性乳房肥大的女性参加了为期12周的减肥计划。所有女性都希望进行乳房缩小手术,并积极进行术前减肥。前8周采用每日提供800千卡热量的配方饮食,在随后的4周重新引入常规食物,将摄入量增加到每日1200千卡。五名女性完成了试验,体重减轻中位数(范围)为10.2(6.5; 19)kg。初始乳房体积为每侧乳房1100 - 2500 mL,干预后减少了300(200; 500)mL;相当于约19%。减肥后腰围、臀围、上臂围和胸围均显著减小。在研究结束时,所有女性仍有症状性乳房肥大,需要进行乳房缩小手术。两个月后进行了手术。为期12周的强化术前减肥计划使肥胖女性能够进行乳房缩小手术。在乳房肥大的女性中,乳房大小的减小比例大于总体重的减轻比例。