Tang Zunyi, Tamura Toshiyo, Sekine Masaki, Huang Ming, Chen Wenxi, Yoshida Masaki, Sakatani Kaoru, Kobayashi Hiroshi, Kanaya Shigehiko
IEEE J Biomed Health Inform. 2017 Sep;21(5):1194-1205. doi: 10.1109/JBHI.2016.2614962. Epub 2016 Oct 4.
In this paper, we present an unobtrusive cuffless blood pressure (BP) monitoring system based on pulse arrival time (PAT) for facilitating long-term home BP monitoring. The proposed system consists of an electrocardiograph (ECG), a photoplethysmograph (PPG), and a control circuit with a Bluetooth module, all of which are mounted on a common armchair to measure ECG and PPG signals from users while sitting on the armchair in order to calculate continuous PAT. Considering the good linear correlation of systolic BP (SBP) and the nonlinear correlation of diastolic BP (DBP) with PAT, a new BP estimation method was proposed. Ten subjects underwent BP monitoring experiments involving stationary sitting on a chair, lying on a bed, and pedaling using an ergometer in order to assess the accuracy of the estimated BP. A cuff-type BP monitor was used as reference in the experiments. Results showed that the mean difference of the estimated SBP and DBP was within 0.2 ± 5.8 mmHg ( p < 0.00001) and 0.4 ± 5.7 mmHg ( p < 0.00001), respectively, and the mean absolute difference of the estimated SBP and DBP were 4.4 and 4.6 mmHg, respectively, compared to references. Additionally, five subjects participated in data collections consisting of sitting on a chair twice a day for one month. Compared to the reference, the difference did not obviously increase along with time, even though individualized calibration was executed only once at the beginning. These results suggest that the proposed system has quite the potential for long-term home BP monitoring.
在本文中，我们提出了一种基于脉搏波传导时间（PAT）的无创无袖带血压监测系统，以促进长期家庭血压监测。该系统由一台心电图仪（ECG）、一台光电容积脉搏波描记仪（PPG）以及一个带有蓝牙模块的控制电路组成，所有这些组件都安装在一把普通的扶手椅上，用于在用户坐在扶手椅上时测量其心电图和光电容积脉搏波信号，从而计算连续的脉搏波传导时间。考虑到收缩压（SBP）与脉搏波传导时间具有良好的线性相关性，而舒张压（DBP）与脉搏波传导时间具有非线性相关性，我们提出了一种新的血压估计方法。十名受试者进行了血压监测实验，包括静坐在椅子上、躺在床上以及使用测力计蹬车，以评估估计血压的准确性。实验中使用袖带式血压监测仪作为参考。结果表明，估计的收缩压和舒张压与参考值相比，平均差值分别在0.2±5.8 mmHg（p<0.00001）和0.4±5.7 mmHg（p<0.00001）以内，估计的收缩压和舒张压的平均绝对差值分别为4.4 mmHg和4.6 mmHg。此外，五名受试者参与了数据收集，每天坐在椅子上两次，持续一个月。与参考值相比，尽管仅在开始时进行了一次个性化校准，但差值并未随时间明显增加。这些结果表明，所提出的系统在长期家庭血压监测方面具有很大的潜力。
