Li Michael H, Yadollahi Azadeh, Taati Babak
IEEE J Biomed Health Inform. 2017 Sep;21(5):1367-1375. doi: 10.1109/JBHI.2016.2567298. Epub 2016 May 11.
Individuals with obstructive sleep apnea (OSA) can experience partial or complete collapse of the upper airway during sleep. This condition affects between 10-17% of adult men and 3-9% of adult women, requiring arousal to resume regular breathing. Frequent arousals disrupt proper sleeping patterns and cause daytime sleepiness. Untreated OSA has been linked to serious medical issues including cardiovascular disease and diabetes. Unfortunately, diagnosis rates are low (∼20%) and current sleep monitoring options are expensive, time consuming, and uncomfortable. Toward the development of a convenient, noncontact OSA monitoring system, this paper presents a simple, computer vision-based method to monitor cardiopulmonary signals (respiratory and heart rates) during sleep. System testing was performed with 17 healthy participants in five different simulated sleep positions. To monitor cardiopulmonary rates, distinctive points are automatically detected and tracked in infrared image sequences. Blind source separation is applied to extract candidate signals of interest. The optimal respiratory and heart rates are determined using periodicity measures based on spectral analysis. Estimates were validated by comparison to polysomnography recordings. The system achieved a mean percentage error of 3.4% and 5.0% for respiratory rate and heart rate, respectively. This study represents an important step in building an accessible, unobtrusive solution for sleep apnea diagnosis.
患有阻塞性睡眠呼吸暂停(OSA)的个体在睡眠期间可能会经历上呼吸道部分或完全塌陷。这种情况在10%至17%的成年男性和3%至9%的成年女性中存在,需要唤醒以恢复正常呼吸。频繁的唤醒会扰乱正常的睡眠模式并导致日间嗜睡。未经治疗的OSA与包括心血管疾病和糖尿病在内的严重医疗问题有关。不幸的是,诊断率很低(约20%),并且当前的睡眠监测选项昂贵、耗时且不舒适。为了开发一种方便、非接触式的OSA监测系统,本文提出了一种基于计算机视觉的简单方法,用于在睡眠期间监测心肺信号(呼吸和心率)。对17名健康参与者在五种不同的模拟睡眠姿势下进行了系统测试。为了监测心肺率,在红外图像序列中自动检测并跟踪特征点。应用盲源分离来提取感兴趣的候选信号。使用基于频谱分析的周期性测量来确定最佳呼吸率和心率。通过与多导睡眠图记录进行比较来验证估计值。该系统的呼吸率和心率平均百分比误差分别为3.4%和5.0%。这项研究是构建一种可及、不引人注意的睡眠呼吸暂停诊断解决方案的重要一步。