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Current controversies in radiotherapy for breast cancer.乳腺癌放射治疗中的当前争议
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本文引用的文献

1
An international randomised controlled trial to compare TARGeted Intraoperative radioTherapy (TARGIT) with conventional postoperative radiotherapy after breast-conserving surgery for women with early-stage breast cancer (the TARGIT-A trial).一项国际随机对照试验，旨在比较早期乳腺癌女性保乳手术后靶向术中放疗（TARGIT）与传统术后放疗（TARGIT-A试验）。
Health Technol Assess. 2016 Sep;20(73):1-188. doi: 10.3310/hta20730.
2
Locoregional Recurrence After Sentinel Lymph Node Dissection With or Without Axillary Dissection in Patients With Sentinel Lymph Node Metastases: Long-term Follow-up From the American College of Surgeons Oncology Group (Alliance) ACOSOG Z0011 Randomized Trial.前哨淋巴结转移患者行前哨淋巴结清扫术加或不加腋窝清扫术后的局部区域复发：美国外科医师学会肿瘤学组（联盟）ACOSOG Z0011随机试验的长期随访
Ann Surg. 2016 Sep;264(3):413-20. doi: 10.1097/SLA.0000000000001863.
3
Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials.早期乳腺癌局部乳腺照射降低死亡率：随机试验的荟萃分析
Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):259-265. doi: 10.1016/j.ijrobp.2016.05.008. Epub 2016 May 13.
4
Do LORIS Trial Eligibility Criteria Identify a Ductal Carcinoma In Situ Patient Population at Low Risk of Upgrade to Invasive Carcinoma?LORIS试验的入选标准能否识别出原位导管癌患者中升级为浸润性癌风险较低的人群？
Ann Surg Oncol. 2016 Oct;23(11):3487-3493. doi: 10.1245/s10434-016-5268-2. Epub 2016 May 12.
5
DEGRO practical guidelines for radiotherapy of breast cancer VI: therapy of locoregional breast cancer recurrences.DEGRO乳腺癌放疗实用指南VI：局部区域乳腺癌复发的治疗
Strahlenther Onkol. 2016 Apr;192(4):199-208. doi: 10.1007/s00066-015-0939-7. Epub 2016 Mar 1.
6
Patient Prognostic Score and Associations With Survival Improvement Offered by Radiotherapy After Breast-Conserving Surgery for Ductal Carcinoma In Situ: A Population-Based Longitudinal Cohort Study.保乳手术后导管原位癌患者的预后评分及放疗对生存改善的影响：一项基于人群的纵向队列研究。
J Clin Oncol. 2016 Apr 10;34(11):1190-6. doi: 10.1200/JCO.2015.65.1869. Epub 2016 Feb 1.
7
CLINICAL DECISIONS. Ductal Carcinoma In Situ.临床决策。导管原位癌。
N Engl J Med. 2016 Jan 28;374(4):390-2. doi: 10.1056/NEJMclde1512213.
8
Adjuvant radiation therapy of regional lymph nodes in breast cancer - a meta-analysis of randomized trials- an update.乳腺癌区域淋巴结的辅助放疗——随机试验的荟萃分析——更新版
Radiat Oncol. 2015 Dec 21;10:258. doi: 10.1186/s13014-015-0568-4.
9
Radiotherapy of Ductal Carcinoma In Situ.导管原位癌的放射治疗
Breast Care (Basel). 2015 Aug;10(4):259-64. doi: 10.1159/000437452. Epub 2015 Aug 19.
10
Radiotherapy of the Lymphatic Pathways in Early Breast Cancer.早期乳腺癌淋巴途径的放射治疗
Breast Care (Basel). 2015 Aug;10(4):254-8. doi: 10.1159/000438662. Epub 2015 Aug 19.

乳腺癌放射治疗中的当前争议

Current controversies in radiotherapy for breast cancer.

作者信息

Krug David, Baumann René, Budach Wilfried, Dunst Jürgen, Feyer Petra, Fietkau Rainer, Haase Wulf, Harms Wolfgang, Piroth Marc D, Sautter-Bihl Marie-Luise, Sedlmayer Felix, Souchon Rainer, Wenz Frederik, Sauer Rolf

机构信息

Department of Radiation Oncology, University Hospital Heidelberg and National Center for Radiation Research in Oncology (NCRO), Heidelberg, Germany.

University Hospital Schleswig-Holstein, Kiel, Germany.

出版信息

Radiat Oncol. 2017 Jan 23;12(1):25. doi: 10.1186/s13014-017-0766-3.

DOI:10.1186/s13014-017-0766-3
PMID:28114948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5259946/
Abstract

Multimodal treatment approaches have substantially improved the outcome of breast cancer patients in the last decades. Radiotherapy is an integral component of multimodal treatment concepts used in curative and palliative intention in numerous clinical situations from precursor lesions such as ductal carcinoma in situ (DCIS) to advanced breast cancer. This review addresses current controversial topics in radiotherapy with special consideration of DCIS, accelerated partial breast irradiation (APBI) and regional nodal irradiation (RNI) and provides an update on the clinical practice guidelines of the Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO).

摘要

在过去几十年中，多模式治疗方法显著改善了乳腺癌患者的治疗效果。放射治疗是多模式治疗理念的一个组成部分，在从原位导管癌（DCIS）等前驱病变到晚期乳腺癌的众多临床情况下，用于根治性和姑息性治疗目的。本综述探讨了放射治疗中当前存在争议的话题，特别考虑了DCIS、加速部分乳腺照射（APBI）和区域淋巴结照射（RNI），并提供了德国放射肿瘤学会（DEGRO）乳腺癌专家小组临床实践指南的最新情况。