Barbera Cinzia, Milito Pamela, Punturieri Michele, Asti Emanuele, Bonavina Luigi
Anesthesiology Unit.
Department of General Surgery, IRCCS Policlinico San Donato, University of Milan Medical School, Milano, Italy.
J Pain Res. 2017 Jan 4;10:73-77. doi: 10.2147/JPR.S121441. eCollection 2017.
Pain is a major limiting factor in patient's recovery from major thoracic surgical procedures. Thoracic epidural analgesia (TEA), the current gold standard of perioperative management, has contraindications, can technically fail, and carries a risk of complications such as epidural abscess and spinal hematoma. The ultrasound-guided serratus anterior plane (SAP) block is a promising regional analgesia technique.
Since the anatomic space involved in the SAP block corresponds to the area exposed by the surgeon during right posterolateral thoracotomy, we investigated the feasibility of a "surgically guided" continuous SAP block as an alternative to TEA in selected esophagectomy patients.
This was a pilot case-series study.
This study was carried out in a tertiary-care university hospital.
The demographic and clinical data of patients in whom the continuous SAP block was performed were retrieved from a prospectively maintained database of hybrid (laparoscopy plus right thoracotomy) Ivor Lewis esophagectomy. The SAP block was performed upon closure of the thoracotomy incision using a 19-gauge catheter tunnelized subcutaneously and positioned in the deep plane between the serratus anterior muscle and the ribs. A bolus dose of 30 mL of levobupivacaine 0.25% was injected, followed by a continuous infusion of the 0.125% solution at 7 mL/h until postoperative day 4.
Between January 2016 and July 2016, seven (20%) out of 37 esophagectomy patients underwent a SAP block rather than TEA for the following reasons: inability to insert the epidural catheter, antiaggregation or anticoagulant therapy, or unplanned thoracotomy. The procedure was uneventful in all patients. Only two patients required rescue analgesia on day 1.
Continuous SAP block under direct vision is feasible and safe. This novel "surgically guided" application of the SAP block may be useful in case of failure or contraindications to TEA.
疼痛是胸外科大手术患者康复的主要限制因素。胸段硬膜外镇痛(TEA)是围手术期管理的当前金标准,但存在禁忌证,技术上可能失败,且有硬膜外脓肿和脊髓血肿等并发症风险。超声引导下前锯肌平面(SAP)阻滞是一种有前景的区域镇痛技术。
由于SAP阻滞涉及的解剖间隙与右后外侧开胸手术中外科医生暴露的区域相对应,我们研究了“手术引导”下连续SAP阻滞作为TEA替代方法用于特定食管癌切除术患者的可行性。
这是一项前瞻性病例系列研究。
本研究在一家三级大学医院进行。
从前瞻性维护的杂交(腹腔镜加右开胸)艾弗·刘易斯食管癌切除术数据库中检索接受连续SAP阻滞患者的人口统计学和临床数据。在关闭开胸切口时进行SAP阻滞,使用19号导管经皮下隧道置入,置于前锯肌和肋骨之间的深层平面。注入30 mL 0.25%左布比卡因的推注剂量,随后以每小时7 mL的速度持续输注0.125%溶液,直至术后第4天。
2016年1月至2016年7月,37例食管癌切除术患者中有7例(20%)因以下原因接受了SAP阻滞而非TEA:无法插入硬膜外导管、抗聚集或抗凝治疗,或计划外开胸手术。所有患者手术过程均顺利。仅2例患者在第1天需要补救镇痛。
直视下连续SAP阻滞可行且安全。这种新颖的“手术引导”下的SAP阻滞应用在TEA失败或有禁忌证的情况下可能有用。