食用核桃油对2型糖尿病患者血糖的影响。
The Effect of Walnut Oil Consumption on Blood Sugar in Patients With Diabetes Mellitus Type 2.
作者信息
Zibaeenezhad Mohammadjavad, Aghasadeghi Kamran, Hakimi Hossein, Yarmohammadi Hassan, Nikaein Farzad
机构信息
Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, IR Iran.
出版信息
Int J Endocrinol Metab. 2016 Jul 24;14(3):e34889. doi: 10.5812/ijem.34889. eCollection 2016 Jul.
BACKGROUND
Prevalence of diabetes mellitus type 2 (DM) is increasing globally. Considering the potential role of poly-unsaturated fatty acids in prevention of DM type 2 and lipid profiles improvement, some studies have been carried out on walnut. However, there are no studies on control of blood sugar in DM type 2 patients using walnut.
OBJECTIVES
The current study aimed to evaluate the effect of walnut oil on blood sugar in DM type 2 patients.
METHODS
This randomized control clinical trial was performed on 100 patients with DM type 2. For the experiment group (n = 50), walnut oil (15 g/day for three months) was added to their diet, while the control group (n = 50) did not undergo any interventions. Before initiation of the experiment and after the experiment, the systolic and diastolic blood pressure (SBP and DBP) levels, fasting blood sugar (FBS) and HbA1c were measured.
RESULTS
The two groups were not significantly different for SBP, DBP, body weight, and Body Mass Index. HbA1c level decreased significantly in the experiment group by 7.86% ± 21.97 (P = 0.005) from 7.00 ± 1.08 before the intervention to 6.37 ± 1.29 after the intervention. Also, FBS level decreased significantly by 8.24% ± 16.77 (P = 0.001); from 158.37 ± 48.16 before the intervention to 137.91 ± 23.24 after the intervention in the experimental group. These changes in the control group were not significant.
CONCLUSIONS
Consumption of walnut oil (15 g/day for three months) was shown to improve blood glucose level but, no changes were noted for bodyweight and blood pressure in type two diabetic patients.
背景
2型糖尿病（DM）在全球的患病率正在上升。考虑到多不饱和脂肪酸在预防2型糖尿病和改善血脂方面的潜在作用，已经对核桃进行了一些研究。然而，尚未有关于使用核桃控制2型糖尿病患者血糖的研究。
目的
本研究旨在评估核桃油对2型糖尿病患者血糖的影响。
方法
本随机对照临床试验对100例2型糖尿病患者进行。实验组（n = 50）在饮食中添加核桃油（每天15克，持续三个月），而对照组（n = 50）未接受任何干预。在实验开始前和实验结束后，测量收缩压和舒张压（SBP和DBP）水平、空腹血糖（FBS）和糖化血红蛋白（HbA1c）。
结果
两组在SBP、DBP、体重和体重指数方面无显著差异。实验组的HbA1c水平从干预前的7.00±1.08显著下降了7.86%±21.97（P = 0.005），至干预后的6.37±1.29。此外，实验组的FBS水平显著下降了8.24%±16.77（P = 0.001）；从干预前的158.37±48.1到干预后的137.91±23.24。对照组的这些变化不显著。
结论
食用核桃油（每天15克，持续三个月）可改善2型糖尿病患者的血糖水平，但体重和血压无变化。
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