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影响B型(IIIb型)主动脉夹层胸段血管腔内主动脉修复术后主动脉最佳重塑的因素。

Factors Affecting Optimal Aortic Remodeling After Thoracic Endovascular Aortic Repair of Type B (IIIb) Aortic Dissection.

作者信息

Chen I-Ming, Chen Po-Lin, Huang Chun-Yang, Weng Shih-Hsien, Chen Wei-Yuan, Shih Chun-Che

机构信息

Institute of Clinical Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan.

Department of Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan.

出版信息

Cardiovasc Intervent Radiol. 2017 May;40(5):671-681. doi: 10.1007/s00270-017-1563-y. Epub 2017 Jan 23.

Abstract

PURPOSE

The purpose of this study was to determine factors associated with entire aortic remodeling after thoracic endovascular aortic repair (TEVAR) in patients with type B dissection.

MATERIALS AND METHODS

The patients with type B (IIIb) dissections who underwent TEVAR from 2006 to 2013 with minimum of 2 years of follow-up computed tomography data were retrospectively reviewed. Based on the status of false lumen remodeling of entire aorta, patients were divided into three groups: complete regression, total thrombosis, and inadequate regression with patent abdominal false lumen.

RESULTS

A total of 90 patients (72 males, 18 females; mean age 56.6 ± 16.4 years) were included and divided into the complete regression (n = 22), total thrombosis (n = 18), and inadequate regression (n = 50) groups. Multivariate logistic regression analysis indicated that dissection extension to iliac arteries, increased preoperative number of dissection tear over abdominal aorta, and decreased preoperative abdominal aorta bifurcation true lumen ratio, as compared between the inadequate and complete regression groups, were associated with a persistent false lumen (odds ratio = 33.33, 2.304, and 0.021; all, p ≤ 0.012). Comparison of 6, 12, and 24 months postoperative data revealed no significant differences at any level, suggesting that the true lumen area ratio might not change after 6 months postoperatively.

CONCLUSIONS

Increased preoperative numbers of dissection tear around the abdominal visceral branches, dissection extension to the iliac arteries, and decreased preoperative true lumen area ratio of abdominal aorta are predictive of entire aortic remodeling after TEVAR in patients with type B dissection.

LEVEL OF EVIDENCE

III.

摘要

目的

本研究旨在确定B型夹层患者经胸腔内血管主动脉修复术(TEVAR)后全主动脉重塑的相关因素。

材料与方法

回顾性分析2006年至2013年接受TEVAR且有至少2年随访计算机断层扫描数据的B型(IIIb型)夹层患者。根据全主动脉假腔重塑情况,将患者分为三组:完全消退、完全血栓形成和腹主动脉假腔未完全消退且仍通畅。

结果

共纳入90例患者(男性72例,女性18例;平均年龄56.6±16.4岁),分为完全消退组(n = 22)、完全血栓形成组(n = 18)和未完全消退组(n = 50)。多因素逻辑回归分析表明,与未完全消退组和完全消退组相比,夹层延伸至髂动脉、术前腹主动脉夹层撕裂数量增加以及术前腹主动脉分叉处真腔比例降低与持续假腔相关(比值比分别为33.33、2.304和0.021;均p≤0.012)。术后6、12和24个月数据比较显示,各水平均无显著差异,提示术后6个月后真腔面积比例可能无变化。

结论

术前腹内脏器分支周围夹层撕裂数量增加、夹层延伸至髂动脉以及术前腹主动脉真腔面积比例降低可预测B型夹层患者TEVAR术后的全主动脉重塑。

证据级别

III级。

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