Suppr超能文献

儿科中毒受害者中的反复中毒情况。

Recurrent poisonings among paediatric poisoning victims.

作者信息

Litovitz T L, Flagler S L, Manoguerra A S, Veltri J C, Wright L

机构信息

National Capital Poison Center, Georgetown University Hospital, Washington, D.C.

出版信息

Med Toxicol Adverse Drug Exp. 1989 Sep-Oct;4(5):381-6. doi: 10.1007/BF03259919.

Abstract

A study of 1943 potentially toxic ingestions occurring in children under 6 years of age was conducted by 3 geographically and demographically diverse poison centres to determine the incidence of exposures to poison. Of the total group, 30.1% indicated that the child had experienced a prior poison exposure (12.0% in children under 1 year of age, and 41.3% of children between the ages of 3 and 5 years). Most repeaters (68.9%) experienced only 1 prior ingestion (range 1 to 15). Two prior ingestions were reported in 17.6% of repeaters; 3 prior ingestions in 4.4%. A profound effect of age on type of substance ingested was observed, with drugs accounting for 11.0% of ingestions in children under the age of 1 year, 23.2% in 1-year-old, and 49.9% in 2- to 5-year-old. A corresponding age-related decline in ingestions of household and personal care products was also noted. Although less marked than the age effect, a statistically significant propensity to re-ingest similar types of poisons was observed. Among repeaters, those with a prior ingestion of a drug subsequently ingested another drug 1.49 times more frequently than expected. A similar trend was observed with products (1.24 times more frequently) and plants (2.00 times more frequently).

摘要

三个地理位置和人口结构各异的中毒控制中心对1943例6岁以下儿童潜在中毒性摄入事件进行了研究,以确定中毒暴露的发生率。在整个研究组中,30.1%的儿童表示曾有过中毒暴露经历(1岁以下儿童为12.0%,3至5岁儿童为41.3%)。大多数有过中毒经历的儿童(68.9%)之前仅发生过1次摄入事件(范围为1至15次)。17.6%的有过中毒经历的儿童报告有过2次之前的摄入事件;4.4%的儿童有过3次之前的摄入事件。研究观察到年龄对摄入物质类型有显著影响,1岁以下儿童摄入药物的比例为11.0%,1岁儿童为23.2%,2至5岁儿童为49.9%。家庭和个人护理产品的摄入量也呈现出相应的与年龄相关的下降趋势。虽然不如年龄影响那么明显,但观察到再次摄入类似类型毒物的倾向具有统计学意义。在有过中毒经历的儿童中,之前摄入过药物的儿童随后摄入另一种药物的频率比预期高1.49倍。产品(高1.24倍)和植物(高2.00倍)也观察到类似趋势。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验