Copeland William E, Hill Sherika, Costello E Jane, Shanahan Lilly
Duke University, Durham, NC.
Duke University, Durham, NC.
J Am Acad Child Adolesc Psychiatry. 2017 Feb;56(2):124-132.e2. doi: 10.1016/j.jaac.2016.11.006. Epub 2016 Nov 25.
Recent changes in DSM criteria require new documentation of the prevalence and developmental sequences of cannabis use disorder (CUD). The goal of this study was to investigate the early course of DSM-5 CUD and its overlap with DSM-IV and consumption constructs in a community-representative sample of American Indians.
Data came from the prospective, longitudinal, population-based Great Smoky Mountains Study in North Carolina (N = 1,420, including 349 American Indians). Cannabis use and disorder were assessed during yearly interviews from 9 to 16 years of age and at 19, 21, 26, and 30 years of age (up to 11 assessments per participant from 1993 through 2015).
By 30 years of age, approximately 70% of participants had used cannabis, 34% had used cannabis daily, and 18% had met criteria for DSM-5 CUD. Approximately 1 in 4 cannabis users met criteria for CUD at some point. Those who met criteria initiated use more than 2 years previously (at 13.3 years old) compared with other users. Despite higher risks from increased poverty, American Indians' patterns of use were similar to those of the rest of the sample. Concordance between DSM-5 CUD and DSM-IV abuse or dependence was substantial but was even higher between DSM-5 CUD and daily use.
It was common to have used cannabis daily or to have met criteria for DSM-5 CUD by adulthood. DSM-5 CUD was an improvement over DSM-IV diagnostic constructs by raising the threshold for diagnosis.
《精神疾病诊断与统计手册》(DSM)标准的近期变化要求对大麻使用障碍(CUD)的患病率和发展顺序进行新的记录。本研究的目的是在具有社区代表性的美国印第安人样本中,调查DSM-5中CUD的早期病程及其与DSM-IV和消费结构的重叠情况。
数据来自北卡罗来纳州基于人群的前瞻性纵向大烟山研究(N = 1420,其中包括349名美国印第安人)。在9至16岁期间以及19、21、26和30岁时(从1993年至2015年,每位参与者最多进行11次评估),通过年度访谈评估大麻使用情况和障碍。
到30岁时,约70%的参与者使用过大麻,34%的参与者每天使用大麻,18%的参与者符合DSM-5中CUD的标准。约四分之一的大麻使用者在某个时间点符合CUD的标准。与其他使用者相比,符合标准的使用者在两年多以前(13.3岁)就开始使用大麻。尽管贫困加剧带来了更高的风险,但美国印第安人的使用模式与样本中的其他人群相似。DSM-5中CUD与DSM-IV滥用或依赖之间的一致性很高,但DSM-5中CUD与每日使用之间的一致性更高。
到成年期时,每天使用大麻或符合DSM-5中CUD的标准很常见。DSM-5中CUD通过提高诊断阈值,比DSM-IV诊断结构有所改进。