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美国成年人在大麻使用日益增加的时期出现大麻使用障碍。

Cannabis use disorders among adults in the United States during a time of increasing use of cannabis.

机构信息

National Institute on Drug Abuse, National Institutes of Health, 6001 Executive Blvd., Bethesda, MD, 20892, USA.

Substance Abuse and Mental Health Services Administration, 5600 Fishers Lane, Rockville, MD, 20857, USA.

出版信息

Drug Alcohol Depend. 2019 Nov 1;204:107468. doi: 10.1016/j.drugalcdep.2019.05.008. Epub 2019 Sep 12.

Abstract

BACKGROUND

Using U.S. National Surveys on Drug Use and Health (NSDUH) data, researchers found that prevalence of cannabis use among adults increased in recent years, but prevalence of DSM-IV cannabis use disorder (CUD) was stable. Examining trends of all individual CUD criteria and of CUD severity may elucidate reasons for the lack of increases in CUD.

METHODS

Data were from 749,500 persons aged 18 or older who participated in the 2002-2017 NSDUH. Descriptive analyses and logistic regressions were applied.

RESULTS

Among adults during 2002-2017, past-year prevalence of DSM-IV CUD remained stable at 1.5% to 1.4%, but cannabis use increased from 10.4% to 15.3%, daily/near daily use increased from 1.9% to 4.2%, and mild DSM-5 CUD increased from 1.4% to 1.9%. Among adult cannabis users, past-year prevalence of DSM-IV CUD decreased from 14.8% to 9.3%, daily/near daily use increased from 18.0% to 27.2%, and DSM-5 moderate (4-5 criteria) and severe (6+ criteria) CUD decreased from 4.3% to 3.1% and from 2.4% to 1.3%, respectively. Examining trends in individual CUD criteria during 2002-2017 among adults overall revealed increases in two criteria (tolerance; spending a lot of time getting/using cannabis or getting over cannabis effects) and decreases/no changes in other criteria; among adult cannabis users, there was no change in one criterion (tolerance) and decreases in other criteria.

CONCLUSIONS

DSM-5's single dimension CUD measure may be more sensitive to diagnosis prevalence changes than the separate DSM-IV cannabis dependence and abuse categories. Future diagnostic approaches to assessing CUD may benefit from quantitatively oriented criteria.

摘要

背景

利用美国国家药物使用与健康调查(NSDUH)的数据,研究人员发现,近年来成年人中大麻使用的流行率有所增加,但 DSM-IV 大麻使用障碍(CUD)的流行率保持稳定。检查所有个体 CUD 标准和 CUD 严重程度的趋势,可能可以阐明 CUD 发病率没有增加的原因。

方法

数据来自于 749500 名年龄在 18 岁或以上的参加了 2002-2017 年 NSDUH 的人群。应用描述性分析和逻辑回归。

结果

在 2002-2017 年期间的成年人中,DSM-IV CUD 的过去一年流行率保持在 1.5%至 1.4%不变,但大麻使用从 10.4%增加到 15.3%,每日/近乎每日使用从 1.9%增加到 4.2%,轻度 DSM-5 CUD 从 1.4%增加到 1.9%。在成年大麻使用者中,DSM-IV CUD 的过去一年流行率从 14.8%下降到 9.3%,每日/近乎每日使用从 18.0%增加到 27.2%,DSM-5 中度(4-5 项标准)和重度(6+项标准)CUD 从 4.3%下降到 3.1%和从 2.4%下降到 1.3%。在 2002-2017 年期间,对所有成年人的个体 CUD 标准趋势进行检查发现,有两个标准(耐受性;花费大量时间获取/使用大麻或摆脱大麻影响)增加,而其他标准减少/没有变化;在成年大麻使用者中,一个标准(耐受性)没有变化,其他标准减少。

结论

DSM-5 的单一维度 CUD 测量方法可能比单独的 DSM-IV 大麻依赖和滥用类别更能灵敏地反映诊断的流行率变化。未来评估 CUD 的诊断方法可能受益于定量导向的标准。

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