Bartels Wibke, Buck Dana, Glos Martin, Fietze Ingo, Penzel Thomas
Interdisciplinary Center of Sleep Medicine, Department of Cardiology, Charité Universitätsmedizin Berlin, Charité Campus Mitte, Charitéplatz 1, Berlin 10117, Germany.
Interdisciplinary Center of Sleep Medicine, Department of Cardiology, Charité Universitätsmedizin Berlin, Charité Campus Mitte, Charitéplatz 1, Berlin 10117, Germany; Department of Oto-Rhino-Laryngology, Charité Universitätsmedizin Berlin, Charité Campus Mitte, Charitéplatz 1, Berlin 10117, Germany.
Sleep Med Clin. 2016 Dec;11(4):435-444. doi: 10.1016/j.jsmc.2016.08.009. Epub 2016 Oct 27.
Autonomic arousal at the end of sleep apnea events are not well-explored. We prospectively studied 20 patients with obstructive sleep apnea (OSA) and 24 healthy volunteers for 2 nights with cardiorespiratory polysomnography and continuous noninvasive blood pressure (Portapres). Recordings were scored visually for cortical and autonomic arousal. In the OSA group, 2151 cortical arousals and in the controls 1089 cortical arousals were scored. Respiratory arousal caused most frequently an increase of highest mean arterial blood pressure in patients and controls. A useful definition for autonomic arousal for OSA and controls based on blood pressure and heart rate analysis was developed.
睡眠呼吸暂停事件结束时的自主神经唤醒尚未得到充分研究。我们前瞻性地对20例阻塞性睡眠呼吸暂停（OSA）患者和24名健康志愿者进行了为期两晚的心肺多导睡眠图和连续无创血压（Portapres）监测。通过视觉对记录进行皮质和自主神经唤醒评分。在OSA组中，记录到2151次皮质唤醒，对照组中记录到1089次皮质唤醒。呼吸唤醒在患者和对照组中最常导致最高平均动脉血压升高。基于血压和心率分析，为OSA患者和对照组自主神经唤醒制定了一个有用的定义。
