Park Nicollet Clinic and HealthPartners Institute, HealthPartners Inc., Minneapolis, MN, USA; Division of Health Policy and Management, University of Minnesota, Minneapolis, MN, USA.
University of Western Australia School of Medicine and Pharmacology, Sir Charles Gairdner Hospital Unit, Perth, Australia; Centre for Kidney Research, Children's Hospital at Westmead, School of Public Health, Sydney Medical School, The University of Sydney, Sydney, Australia.
Bone. 2017 Nov;104:91-100. doi: 10.1016/j.bone.2017.01.025. Epub 2017 Jan 22.
Abdominal aortic calcification (AAC) can be accurately recognized on lateral spine images intended for vertebral fracture assessment, that are obtained with dual-energy X-ray absorptiometry (DXA). Greater amounts of AAC are common in the older population for whom DXA is routinely done, and have been consistently associated with incident atherosclerotic cardiovascular disease (ASCVD) events. AAC has also been associated with incident fractures in some prospective studies, but not in others. However, further research is needed to quantify the extent to which measurement of AAC improves prediction of ASCVD events and its impact on physician and patient ASCVD risk management. Additionally, research to develop better, more precise, automated, quantitative methods of AAC assessment on lateral spine densitometric images will hopefully lead to better prediction of clinical outcomes. In conclusion, although the prime indication for densitometric lateral spine imaging remains vertebral fracture assessment, AAC that is found incidentally on lateral spine images should be reported, so that patients and their health care providers are aware of its presence.
腹主动脉钙化 (AAC) 可以在用于评估椎体骨折的双能 X 射线吸收法 (DXA) 获得的侧位脊柱图像上准确识别。对于常规进行 DXA 的老年人群,AAC 的数量较多,并且与动脉粥样硬化性心血管疾病 (ASCVD) 事件的发生一直相关。在一些前瞻性研究中,AAC 也与骨折的发生有关,但在其他研究中则没有。然而,需要进一步的研究来量化 AAC 测量在多大程度上可以改善 ASCVD 事件的预测及其对医生和患者 ASCVD 风险管理的影响。此外,研究开发更好、更精确、自动、定量的侧位脊柱密度计图像 AAC 评估方法,有望更好地预测临床结果。总之,尽管密度计侧位脊柱成像的主要适应证仍然是评估椎体骨折,但应报告偶然发现的侧位脊柱图像上的 AAC,以便患者及其医疗保健提供者了解其存在。