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本文引用的文献

1
Antibiotic stewardship challenges in the management of community-acquired infections for prevention of escalating antibiotic resistance.社区获得性感染管理中抗生素管理面临的挑战,以预防抗生素耐药性不断升级。
J Glob Antimicrob Resist. 2014 Dec;2(4):245-253. doi: 10.1016/j.jgar.2014.08.002. Epub 2014 Sep 16.
2
Exploring the barriers and facilitators to use of point of care tests in family medicine clinics in the United States.探索美国家庭医学诊所使用即时检验的障碍与促进因素。
BMC Fam Pract. 2016 Nov 3;17(1):149. doi: 10.1186/s12875-016-0549-1.
3
Point-of-care C reactive protein for the diagnosis of lower respiratory tract infection in NHS primary care: a qualitative study of barriers and facilitators to adoption.英国国家医疗服务体系基层医疗中用于诊断下呼吸道感染的即时检测C反应蛋白:一项关于采用障碍与促进因素的定性研究
BMJ Open. 2016 Mar 3;6(3):e009959. doi: 10.1136/bmjopen-2015-009959.
4
Primary care clinician antibiotic prescribing decisions in consultations for children with RTIs: a qualitative interview study.基层医疗临床医生在儿童呼吸道感染咨询中的抗生素处方决策:一项定性访谈研究
Br J Gen Pract. 2016 Mar;66(644):e207-13. doi: 10.3399/bjgp16X683821. Epub 2016 Feb 7.
5
Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention.成人急性呼吸道感染抗生素的合理应用:美国医师学院和疾病控制与预防中心关于高价值医疗保健的建议。
Ann Intern Med. 2016 Mar 15;164(6):425-34. doi: 10.7326/M15-1840. Epub 2016 Jan 19.
6
C-reactive protein point-of-care testing in acutely ill children: a mixed methods study in primary care.急性病患儿的C反应蛋白即时检测:一项初级保健中的混合方法研究
Arch Dis Child. 2016 Apr;101(4):382-5. doi: 10.1136/archdischild-2015-309228. Epub 2016 Jan 12.
7
Antibiotic use for viral acute respiratory tract infections remains common.抗生素用于病毒性急性呼吸道感染仍然很常见。
Am J Manag Care. 2015 Oct 1;21(10):e567-75.
8
Narrative review of primary care point-of-care testing (POCT) and antibacterial use in respiratory tract infection (RTI).初级保健即时检验(POCT)和呼吸道感染(RTI)中抗菌药物使用的叙述性综述。
BMJ Open Respir Res. 2015 May 6;2(1):e000086. doi: 10.1136/bmjresp-2015-000086. eCollection 2015.
9
The added diagnostic value of five different C-reactive protein point-of-care test devices in detecting pneumonia in primary care: A nested case-control study.五种不同即时检测C反应蛋白的设备在基层医疗中检测肺炎的附加诊断价值:一项巢式病例对照研究
Scand J Clin Lab Invest. 2015 Jul;75(4):291-5. doi: 10.3109/00365513.2015.1006136. Epub 2015 Feb 27.
10
Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem.抗菌药物耐药性:抗生素过度使用相关风险及解决措施。
Ther Adv Drug Saf. 2014 Dec;5(6):229-41. doi: 10.1177/2042098614554919.

关于基层医疗临床医生对家庭医学中急性呼吸道感染C反应蛋白即时检测看法的定性研究。

Qualitative study of primary care clinicians' views on point-of-care testing for C-reactive protein for acute respiratory tract infections in family medicine.

作者信息

Hardy Victoria, Thompson Matthew, Keppel Gina A, Alto William, Dirac M Ashworth, Neher Jon, Sanford Christopher, Hornecker Jaime, Cole Allison

机构信息

Department of Family Medicine, University of Washington, Seattle, Washington, USA.

Seattle Indian Health Board, Seattle, Washington, USA.

出版信息

BMJ Open. 2017 Jan 25;7(1):e012503. doi: 10.1136/bmjopen-2016-012503.

DOI:10.1136/bmjopen-2016-012503
PMID:28122829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5278283/
Abstract

OBJECTIVE

To explore clinicians views of the barriers and facilitators to use of C-reactive protein (CRP) point-of-care tests (POCT) in US family medicine clinics for the management of acute respiratory tract infections (ARTIs) in adults.

SETTING

Five family medicine clinics across two US states.

PARTICIPANTS

30 clinicians including 18 physicians, 9 physician residents, 2 physician assistants and 1 nurse practitioner, took part in the study.

DESIGN

A qualitative study using a grounded theory approach to thematically analyse focus group interviews.

RESULTS

These clinicians had limited access to diagnostic tests for patients with ARTI, and very little knowledge of CRP POCT. Three major themes were identified and included the potential clinical role of CRP POCT, concerns related to implementing CRP POCT and evidence needed prior to wider adoption in family medicine. Clinicians believed CRP POCT could support decision-making for some presentations of ARTIs and patient populations when used in conjunction with clinical criteria. Clinicians had concerns about possible overuse and inaccuracy of CRP POCT which they believed might increase antibiotic prescribing rates. Other concerns identified included integration of the test with clinic workflows and cost-effectiveness.

CONCLUSIONS

Clinicians stand at the forefront of antibiotic stewardship efforts, but have few diagnostic tests to help them confidently manage ARTIs. CRP POCT may facilitate some aspects of clinical practice. Incorporating CRP POCT with clinical guidelines may strengthen utility of this test, when there is diagnostic uncertainty.

摘要

目的

探讨临床医生对于在美国家庭医学诊所使用C反应蛋白(CRP)即时检验(POCT)来管理成人急性呼吸道感染(ARTI)的障碍和促进因素的看法。

背景

美国两个州的五家家庭医学诊所。

参与者

30名临床医生参与了研究,其中包括18名医生、9名住院医生、2名医师助理和1名执业护士。

设计

一项采用扎根理论方法对焦点小组访谈进行主题分析的定性研究。

结果

这些临床医生为ARTI患者提供诊断检测的机会有限,并且对CRP POCT了解甚少。确定了三个主要主题,包括CRP POCT的潜在临床作用、与实施CRP POCT相关的担忧以及在家庭医学中更广泛采用之前所需的证据。临床医生认为,CRP POCT与临床标准结合使用时,可为某些ARTI表现和患者群体的决策提供支持。临床医生担心CRP POCT可能会被过度使用且不准确,他们认为这可能会提高抗生素的处方率。其他确定的担忧包括该检测与诊所工作流程的整合以及成本效益。

结论

临床医生处于抗生素管理工作的前沿,但用于帮助他们自信地管理ARTI的诊断检测很少。CRP POCT可能会促进临床实践的某些方面。当存在诊断不确定性时,将CRP POCT与临床指南相结合可能会增强该检测的实用性。