Ardito G, Campanile F C, Diodati A, Furgiuele S, Rabitti C, Di Giovanni V
Minerva Chir. 1989 Aug 31;44(15-16):1791-4.
Personal experience with small cell thyroid tumours is reviewed in the light of recent developments in diagnosis and treatment. All cases were examined by means of immunohistochemical investigation of the lymphocytic and epithelial antigens. In 7 cases in which the production of lymphocytic antigens was confirmed, a primary lymphoma of the thyroid was diagnosed. Immunohistochemical studies of the lymphocytic and epithelial antigens are essential in all small cell thyroid tumours, in order to differentiate between small cell anaplastic carcinomas and thyroid lymphomas. This differentiation is indispensable for the correct choice of treatment and an accurate prognostic assessment. In the case of lymphomas, combined surgical and radiation treatment adjusted to the clinical stage of the tumour is recommended.
根据诊断和治疗方面的最新进展，对小细胞甲状腺肿瘤的个人经验进行了回顾。所有病例均通过淋巴细胞和上皮抗原的免疫组织化学研究进行检查。在7例证实有淋巴细胞抗原产生的病例中，诊断为原发性甲状腺淋巴瘤。对所有小细胞甲状腺肿瘤进行淋巴细胞和上皮抗原的免疫组织化学研究至关重要，以便区分小细胞间变性癌和甲状腺淋巴瘤。这种区分对于正确选择治疗方法和准确的预后评估是必不可少的。对于淋巴瘤，建议根据肿瘤的临床分期进行手术和放疗联合治疗。
