Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University , Wuhan 430079, P. R. China.
Nuffield Department of Clinical Neurosciences, Department of Chemistry, University of Oxford , Oxford OX1 2JD, United Kingdom.
ACS Appl Mater Interfaces. 2017 Feb 15;9(6):5031-5049. doi: 10.1021/acsami.6b16108. Epub 2017 Feb 6.
Aryldiazonium salts as coupling agents for surface chemistry have evidenced their wide applications for the development of sensors. Combined with advances in nanomaterials, current trends in sensor science and a variety of particular advantages of aryldiazonium salt chemistry in sensing have driven the aryldiazonium salt-based sensing strategies to grow at an astonishing pace. This review focuses on the advances in the use of aryldiazonium salts for modifying interfaces in sensors and biosensors during the past decade. It will first summarize the current methods for modification of interfaces with aryldiazonium salts, and then discuss the sensing applications of aryldiazonium salts modified on different transducers (bulky solid electrodes, nanomaterials modified bulky solid electrodes, and nanoparticles). Finally, the challenges and perspectives that aryldiazonium salt chemistry is facing in sensing applications are critically discussed.
芳基重氮盐作为表面化学偶联剂，在传感器的发展中已经证明了其广泛的应用。结合纳米材料的进步，当前传感器科学的趋势以及芳基重氮盐化学在传感中的各种特殊优势，推动了基于芳基重氮盐的传感策略以惊人的速度发展。本文综述了过去十年中芳基重氮盐在修饰传感器和生物传感器界面方面的应用进展。本文首先总结了当前使用芳基重氮盐修饰界面的方法，然后讨论了芳基重氮盐在不同换能器（块状固体电极、纳米材料修饰的块状固体电极和纳米粒子）上的传感应用。最后，本文批判性地讨论了芳基重氮盐化学在传感应用中面临的挑战和展望。
