Celis I M, Kriekaart R L, Aliredjo R P, van Lochem E G, van der Vorst M J D L, Hassing R
Department of Internal Medicine, Rijnstate Medical Centre, Arnhem, the Netherlands.
Neth J Med. 2017 Jan;75(1):27-31.
IgG4-related disease (IgG4-RD) is an increasingly recognised entity characterised by tumefied lesions that can affect multiple organs. Awareness of IgG4-RD is important, as it has been shown to mimic other diseases and may result in irreversible organ damage if not treated. If suspected, immunostaining for IgG4-positive plasma cells is essential for diagnosis and revision of old biopsies may be necessary.
IgG4相关性疾病（IgG4-RD）是一种日益受到认可的疾病实体，其特征为可累及多个器官的肿胀性病变。认识IgG4-RD很重要，因为它已被证实可模仿其他疾病，若不治疗可能导致不可逆的器官损害。如果怀疑患有该病，对IgG4阳性浆细胞进行免疫染色对于诊断至关重要，可能还需要对旧活检标本进行复查。
