Baraliakos X, Fruth M, Kiltz U, Braun J
Rheumazentrum Ruhrgebiet Herne, Claudiusstr. 45, 44649, Herne, Deutschland.
Z Rheumatol. 2017 Mar;76(2):149-162. doi: 10.1007/s00393-016-0252-6.
The diagnosis of axial spondyloarthritis (axSpA) includes classical ankylosing spondylitis (AS) as well as earlier stages and abortive courses of the disease, in which structural alterations have not yet occurred. These are classified as non-radiographic axSpA (nr-axSpa). Inflammatory changes in the entire axial skeleton are characteristic for axSpA and can be visualized by magnetic resonance imaging (MRI), while in most patients structural alterations, such as new bone formation with syndesmophytes and ankylosis develop in the later course of the disease. These bony alterations can best be visualized by conventional radiography and by computed tomography. Certain MRI sequences are nowadays considered as the standard method for depiction of inflammatory changes in axSpA. The introduction of MRI has led to a paradigm shift for this disease because the inflammatory lesions characteristic for the disease can be visualized at an early stage using appropriate MRI sequences.
中轴型脊柱关节炎（axSpA）的诊断包括典型的强直性脊柱炎（AS）以及该疾病的早期阶段和未发展至结构改变的顿挫型病程。这些被归类为非放射学中轴型脊柱关节炎（nr-axSpa）。整个中轴骨骼的炎症性改变是axSpA的特征，可通过磁共振成像（MRI）显示，而在大多数患者中，结构改变，如韧带骨赘和强直等新骨形成在疾病后期出现。这些骨质改变通过传统X线摄影和计算机断层扫描能得到最佳显示。如今，某些MRI序列被视为显示axSpA炎症性改变的标准方法。MRI的引入导致了该疾病的范式转变，因为使用合适的MRI序列可在疾病早期显示出该疾病特有的炎性病变。
