Lader E
N Y State Dent J. 1989 Nov;55(9):46, 48, 50-2.
Due to the high incidence of Lyme disease, the ease with which it can be misdiagnosed, and its potential for causing irreversible neurologic or cardiac complications and fatalities if left untreated, all patients living in known epidemic areas who manifest intractable facial pain, or what appears to be a case of temporomandibular joint syndrome that does not respond to therapy should be tested for Lyme Borelliosis. It should be remembered however, that not all patients with active Lyme disease produce antibodies, and it is thus imperative for the clinician to obtain a detailed patient history with a focused series of questions directed at the known presentations of the disease, with specific emphasis placed on the prior appearance of an ECM lesion.
由于莱姆病发病率高、易被误诊，且若不治疗有导致不可逆神经或心脏并发症及死亡的风险，所有生活在已知疫区且出现顽固性面部疼痛的患者，或疑似颞下颌关节综合征但治疗无反应的患者，都应接受莱姆疏螺旋体病检测。然而，应记住并非所有活动性莱姆病患者都会产生抗体，因此临床医生必须详细询问患者病史，针对性地提出一系列有关该病已知表现的问题，尤其要重点询问此前是否出现过游走性红斑病变。
