Begon E
Service de dermatologie, centre hospitalier général René-Dubos, 6, avenue de l'Ile-de-France, BP 79, 95303 Cergy-Pontoise cedex, France.
Med Mal Infect. 2007 Jul-Aug;37(7-8):422-34. doi: 10.1016/j.medmal.2006.01.026. Epub 2007 Aug 14.
Lyme disease or Lyme borreliosis is the most common tick-transmitted disease in the Northern hemisphere and is caused by Borrelia burgdorferi spirochetes. Lyme disease commonly begins with a characteristic skin lesion, erythema migrans. Weeks or months later, the patients may have neurologic, joint, or cardiac abnormalities. Some patients may still present persistent deep fatigue and various unspecific symptoms after standard courses of antibiotic treatment for Lyme disease. This constellation of symptoms has been variously referred to as "chronic Lyme disease", or "post-Lyme disease syndrome". The first French National Consensus Conference on Lyme Disease was the reason to review all aspects of articular and cardiac manifestations of Lyme disease after a synthesis of recent literature. The involvement of Borrelia species in chronic Lyme disease and other pathologies is discussed.
莱姆病或莱姆疏螺旋体病是北半球最常见的蜱传疾病,由伯氏疏螺旋体引起。莱姆病通常始于一种特征性皮肤病变——游走性红斑。数周或数月后,患者可能出现神经、关节或心脏异常。一些患者在接受莱姆病标准疗程抗生素治疗后,仍可能出现持续的深度疲劳和各种非特异性症状。这一系列症状被不同地称为“慢性莱姆病”或“莱姆病后综合征”。法国首次莱姆病全国共识会议是在综合近期文献后,对莱姆病关节和心脏表现的各个方面进行回顾的契机。文中还讨论了疏螺旋体属在慢性莱姆病和其他病症中的作用。