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安卡非德植物性止血提取物作为杀菌剂的体外疗效

In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent.

作者信息

Metin Bayram, Yilmaz Neziha, Beyhan Yunus Emre, Babür Cahit, Sipahi Mesut, Ede Hüseyin, Intepe Yavuz Selim, Arslan Ergin, Atalay Tugay, Özdamar Mustafa Yaşar

机构信息

Department of Thoracic Surgery, Faculty of Medicine, Bozok University, Yozgat, Turkey.

Department of Infectious Diseases, Faculty of Medicine, Bozok University, Yozgat, Turkey.

出版信息

Iran J Parasitol. 2016 Jul-Sep;11(3):406-410.

PMID:28127348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5256059/
Abstract

BACKGROUND

Hydatid cysts are encountered frequently in regions endemic with livestock. The basic treatment for a hydatid cyst is total surgical removal of the cyst and its inner contents. Hypertonic NaCl or diluted betadine solution are used as germicidal agents for most hydatid surgeries. However, the germicidal efficacy of the Ankaferd Blood Stopper® (ABS) has not been investigated. Thus, we compared the efficacy of ABS for hydatid cysts with that of other germicidal agents.

METHODS

Lung and liver tissues containing hydatid cyst liquid were collected from slaughterhouses. Six samples of each cyst were randomly allocated into different groups as follows: 20% hypertonic NaCl, betadine solution, ABS, 20% liquefied Andazole solution, 0.1% eosin, and distilled water. All groups were examined microscopically at 5, 10, and 15 min after treatment began to determine protoscolece viability rates.

RESULTS

The most efficacious germicidal agent at 5 min was ABS, and betadine and hypertonic NaCl had similar efficacies. Betadine, ABS, and hypertonic NaCl showed similar efficacies at 15 min.

CONCLUSION

ABS was an effective germicidal agent to treat hydatid cysts.

摘要

背景

在畜牧养殖流行地区,包虫囊肿较为常见。包虫囊肿的基本治疗方法是手术完全切除囊肿及其内部内容物。在大多数包虫手术中,高渗氯化钠或稀释的聚维酮碘溶液用作杀菌剂。然而,安卡芬德止血剂(ABS)的杀菌效果尚未得到研究。因此,我们比较了ABS与其他杀菌剂对包虫囊肿的疗效。

方法

从屠宰场收集含有包虫囊液的肺和肝组织。每个囊肿的六个样本被随机分为以下不同组:20%高渗氯化钠、聚维酮碘溶液、ABS、20%液化阿苯达唑溶液、0.1%伊红和蒸馏水。在处理开始后的5分钟、10分钟和15分钟,对所有组进行显微镜检查,以确定原头节存活率。

结果

5分钟时最有效的杀菌剂是ABS,聚维酮碘和高渗氯化钠的效果相似。15分钟时,聚维酮碘、ABS和高渗氯化钠显示出相似的效果。

结论

ABS是治疗包虫囊肿的一种有效杀菌剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8c1/5256059/35319c829f71/IJPA-11-406-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8c1/5256059/35319c829f71/IJPA-11-406-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8c1/5256059/35319c829f71/IJPA-11-406-g001.jpg

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本文引用的文献

1
[Investigation of the germicidal effect of usnic acid, betadine, savlosol, and desderman on the protoscolexes of lung hydatid cysts].[松萝酸、聚维酮碘、萨伏索、地斯德曼对肺包虫囊肿原头蚴的杀菌效果研究]
Turkiye Parazitol Derg. 2007;31(2):101-4.
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