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单极电容射频、电刺激与负压联合作用下的瘢痕重塑

Scar Remodeling with the Association of Monopolar Capacitive Radiofrequency, Electric Stimulation, and Negative Pressure.

作者信息

Nicoletti Giovanni, Perugini Paola, Bellino Sara, Capra Priscilla, Malovini Alberto, Jaber Omar, Tresoldi Marco, Faga Angela

机构信息

1 Plastic and Reconstructive Surgery, Department of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia , Pavia, Italy .

2 Advanced Technologies for Regenerative Medicine and Inductive Surgery Research Center, University of Pavia , Pavia, Italy .

出版信息

Photomed Laser Surg. 2017 May;35(5):246-258. doi: 10.1089/pho.2016.4180. Epub 2017 Jan 24.

Abstract

OBJECTIVE

A study was established to objectively assess the effects of low-intensity electromagnetic and electric stimulation plus negative pressure on mature scars.

BACKGROUND

Radiofrequency plus negative pressure therapy demonstrated a favorable reorganization and regeneration of the collagen and elastic fibers and was proposed for the treatment of cellulitis and skin stretch marks.

METHODS

Twenty-six mature scars in 20 Caucasian patients (15 females and 5 males) were enrolled in the study. The treatments were carried out with a Class I, BF-type electromedical device equipped with a radiofrequency generator, an electric pulse generator, and a vacuum pump twice a week for 3 months. Corneometry, transepidermal water loss, elastometry, colorimetry, and three-dimensional skin surface pattern were objectively assessed with Multi Probe Adapter System MPA and PRIMOS pico. A subjective assessment was carried out with the VAS and PSAS scales. Each scar was compared before and after the treatment and with the skin in the corresponding healthy contralateral anatomical area at the same times.

RESULTS

Reduction of the scar surface wrinkling and overall scar flattening were demonstrated after the treatment. The scar slightly tended to approach the color and elasticity of healthy skin too.

CONCLUSIONS

The combined local treatment of mature scars with low-intensity electromagnetic and electric stimulation in association with negative pressure might suggest a favorable synergic effect on the scar collagen and elastic fiber remodeling.

摘要

目的

开展一项研究以客观评估低强度电磁和电刺激联合负压对成熟瘢痕的影响。

背景

射频联合负压疗法显示出对胶原蛋白和弹性纤维有良好的重组和再生作用,并被提议用于治疗蜂窝织炎和皮肤妊娠纹。

方法

本研究纳入了20例白种人患者(15例女性和5例男性)的26处成熟瘢痕。使用配备射频发生器、电脉冲发生器和真空泵的I类BF型电子医疗设备进行治疗,每周两次,共3个月。使用多探头适配器系统MPA和PRIMOS pico客观评估角质层测量、经表皮水分流失、弹性测量、比色法和三维皮肤表面形态。使用视觉模拟量表(VAS)和患者和观察者瘢痕评估量表(PSAS)进行主观评估。每次治疗前后均对瘢痕进行比较,并同时与相应健康对侧解剖区域的皮肤进行比较。

结果

治疗后瘢痕表面皱纹减少,瘢痕整体变平。瘢痕的颜色和弹性也略微趋于接近健康皮肤。

结论

低强度电磁和电刺激联合负压对成熟瘢痕进行局部治疗,可能对瘢痕胶原蛋白和弹性纤维重塑产生良好的协同作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6e0/5439422/ef013c1078a2/fig-1.jpg

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