Penot Pauline, Brichler Ségolène, Guilleminot Jean, Lascoux-Combe Caroline, Taulera Olivier, Gordien Emmanuel, Leparc-Goffart Isabelle, Molina Jean-Michel
Internal Medicine and Infectious Diseases Department, Andre Gregoire Hospital, Montreuil, France.
Infectious and Tropical Diseases Department, Saint Louis Hospital, Paris, France.
Euro Surveill. 2017 Jan 19;22(3). doi: 10.2807/1560-7917.ES.2017.22.3.30444.
A woman with controlled HIV infection developed in late August 2016 a pruritic rash with fever and conjunctival hyperaemia after a trip to the French Caribbean islands. On day 3 after symptom onset, Zika virus RNA was detected in plasma, urine and vaginal samples with respective viral loads of 3.8, 6.1 and 5.3 log copies/mL. Notably, we demonstrated the presence of infectious Zika virus particles in the vaginal samples by isolation in cell culture.
一名感染得到控制的HIV女性患者于2016年8月下旬前往法属加勒比群岛旅行后,出现了伴有发热和结膜充血的瘙痒性皮疹。症状出现后第3天,在血浆、尿液和阴道样本中检测到寨卡病毒RNA,病毒载量分别为3.8、6.1和5.3 log拷贝/毫升。值得注意的是,我们通过细胞培养分离在阴道样本中证实了有传染性的寨卡病毒颗粒的存在。