Consigny Paul Henri
Centre médical de l'Institut Pasteur, 211 rue de Vaugirard, 75015 Paris, France.
Med Trop Sante Int. 2024 Apr 2;4(2). doi: 10.48327/mtsi.v4i2.2024.502. eCollection 2024 Jun 30.
Zika virus infection, most oft n responsible for a benign arboviral disease or an asymptomatic infection, rarely Guillain-Barré syndrome, can become problematic in pregnant women, due to a risk of fetal malformations, in particular microcephaly linked to its neurotropism. The most recent large-scale epidemic was observed throughout Latin America between 2015 and 2017, causing several hundred thousand cases. Transmission is predominantly vector-borne, but sexual transmission has been described, mainly among travelers, although it undoubtedly accounts for a significant proportion of transmission in epidemic areas. The aim of this review is to describe this sexual transmission, mainly through examples linked to this large-scale epidemic in Latin America, to describe the link with prolonged excretion of infectious viral particles in genital secretions, especially semen but also vaginal secretions, and to highlight possible preventive measures apart from vector transmission, in particular the need for pregnant women or women wishing to become pregnant to avoid visiting countries where circulation of Zika virus is described.
寨卡病毒感染通常引发良性虫媒病毒病或无症状感染,很少导致吉兰-巴雷综合征,但在孕妇中可能会引发问题,因为存在胎儿畸形风险,尤其是与病毒嗜神经性相关的小头畸形。最近一次大规模疫情于2015年至2017年在拉丁美洲出现,造成了几十万病例。传播主要通过病媒,但也有性传播的描述,主要发生在旅行者中,不过在疫区它无疑占传播的很大比例。本综述的目的是描述这种性传播,主要通过与拉丁美洲这次大规模疫情相关的例子,描述其与传染性病毒颗粒在生殖分泌物(特别是精液,但也包括阴道分泌物)中长期排泄的关联,并强调除病媒传播外可能的预防措施,特别是孕妇或希望怀孕的女性需要避免前往有寨卡病毒传播的国家。