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IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of Adult T-cell Leukemia/Lymphoma patients.

作者信息

Dierckx T, Khouri R, Menezes S M, Decanine D, Farre L, Bittencourt A, Vandamme A M, Van Weyenbergh J

机构信息

Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven - University of Leuven, Leuven, Belgium.

Instituto Gonçalo Moniz-FIOCRUZ, Salvador-Bahia, Brazil.

出版信息

Blood Cancer J. 2017 Jan 27;7(1):e519. doi: 10.1038/bcj.2016.126.

DOI:10.1038/bcj.2016.126
PMID:28128792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5301034/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2490/5301034/8a34df0a143c/bcj2016126f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2490/5301034/266605fe953c/bcj2016126f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2490/5301034/8a34df0a143c/bcj2016126f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2490/5301034/266605fe953c/bcj2016126f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2490/5301034/8a34df0a143c/bcj2016126f2.jpg

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PLoS Pathog. 2016 Apr 22;12(4):e1005560. doi: 10.1371/journal.ppat.1005560. eCollection 2016 Apr.
2
Integrated molecular analysis of adult T cell leukemia/lymphoma.成人 T 细胞白血病/淋巴瘤的综合分子分析。
Nat Genet. 2015 Nov;47(11):1304-15. doi: 10.1038/ng.3415. Epub 2015 Oct 5.
3
Therapeutic options for adult T-cell leukemia/lymphoma.
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Nat Aging. 2023 Jun;3(6):722-733. doi: 10.1038/s43587-023-00421-1. Epub 2023 May 22.
4
Interferon Signaling-Dependent Contribution of Glycolysis to Rubella Virus Infection.糖酵解对风疹病毒感染的干扰素信号依赖性贡献。
Pathogens. 2022 May 3;11(5):537. doi: 10.3390/pathogens11050537.
5
Loss and Promoter Hypermethylation Negatively Predict for Immunogenicity in BRCA-Deficient Ovarian Cancer.BRCA 缺陷型卵巢癌中，缺失和启动子超甲基化对免疫原性起负性预测作用。
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