Shlomi Polachek Inbal, Manor Adi, Baumfeld Yael, Bagadia Ashlesha, Polachek Ari, Strous Rael D, Dolev Zipora
*Beer Yaakov-Ness Ziona Mental Health Centre, Beer Yaakov, Israel; †Women's Mental Health Program, Women's College Hospital, Toronto, Canada; ‡Clinical Research Center, Soroka Medical Center, Beer Sheva, Israel; §Psoriatic Arthritis Program, Center for Prognostic Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, ON, Canada; ∥Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv; and ¶Psychiatry Clinic, Herzelia, Israel.
J Nerv Ment Dis. 2017 Apr;205(4):313-317. doi: 10.1097/NMD.0000000000000645.
We aimed to evaluate the association between sex and hospitalization characteristics in psychotic disorders. We identified all acute hospitalizations, between 2010 and 2013, for psychotic disorders in patients younger than 45 and older than 55 years (n = 5411) in the hospital's database. In addition, we identified patients who were prescribed with intramuscular risperidone (n = 280) or clozapine (n = 192) at discharge. The results showed that women younger than 45 years had lower proportions of hospitalizations (33.52% vs. 66.47%) and involuntary hospitalizations (33.85% vs. 45.55%) than did men in the same age group. Women older than 55 years had higher proportions of hospitalizations (57.22% vs. 42.77%) and similar proportion of involuntary hospitalizations. Women younger than 45 years were prescribed similar doses of intramuscular risperidone and lower doses of clozapine (345.8 vs. 380.2 mg) and women older than 55 years were prescribed higher doses of intramuscular risperidone (44.8 vs. 34.4 mg/2 weeks) and clozapine (164.32 vs. 154.5 mg) than were men in the same age group. Women in the reproductive years have better hospitalization characteristics than do men on these measures.
我们旨在评估精神病性障碍中性别与住院特征之间的关联。我们在医院数据库中确定了2010年至2013年间所有45岁以下及55岁以上精神病性障碍患者的急性住院情况(n = 5411)。此外,我们确定了出院时接受肌肉注射利培酮(n = 280)或氯氮平(n = 192)治疗的患者。结果显示,45岁以下女性的住院比例(33.52%对66.47%)和非自愿住院比例(33.85%对45.55%)低于同年龄组男性。55岁以上女性的住院比例较高(57.22%对42.77%),非自愿住院比例相似。45岁以下女性接受的肌肉注射利培酮剂量相似,氯氮平剂量较低(345.8对380.2毫克),55岁以上女性接受的肌肉注射利培酮(44.8对34.4毫克/2周)和氯氮平(164.32对154.5毫克)剂量高于同年龄组男性。在这些指标上,育龄期女性的住院特征优于男性。