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[扁桃体肿瘤的放射治疗。治疗结果及晚期并发症评估]

[Radiotherapy of tonsillar neoplasms. Evaluation of treatment results and late complications].

作者信息

Zajonc-Słowakiewicz A, Maciejewski B, Mistur A

出版信息

Nowotwory. 1989 Jan-Mar;39(1):44-52.

PMID:2813090
Abstract

The aim of this study is to analyse the results of radiation treatment of 72 patients with squamous cell carcinoma of the tonsil, irradiated with 60Co. Three-year local control rates of 80% in T2 stage and 40% in T3 stage were noted. Total doses of 60-65 Gy in T2 lesions and at least 70 Gy in T3 lesions, fractionated in 2.0 Gy fractions, give a high loco-regional control probability. Overall treatment time is an important factor for local control of cancer of the tonsil. With treatment time prolonged over 40-45 days, local control rate decreases rapidly. Neck lymph nodes status influences the response of cancer of the tonsil. It suggests delivery of higher total dose in the region of primary lesion when neck lymph nodes are advanced, in stage N2 and N3 then in N0 a and N1.

摘要

本研究的目的是分析72例扁桃体鳞状细胞癌患者接受钴-60放疗的结果。T2期三年局部控制率为80%,T3期为40%。T2病变的总剂量为60 - 65 Gy,T3病变至少为70 Gy,以2.0 Gy分割,可获得较高的局部区域控制概率。总体治疗时间是扁桃体癌局部控制的重要因素。当治疗时间延长超过40 - 45天时,局部控制率迅速下降。颈部淋巴结状态影响扁桃体癌的反应。这表明当颈部淋巴结处于进展期(N2和N3期)时,与N0a和N1期相比,在原发灶区域应给予更高的总剂量。

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