Department of Medicinal Chemistry, Chia Nan University of Pharmacy and Science, 60, Sec. 1, Erren Rd., Rende Dist., Tainan City 71710, Taiwan.
Department of Environmental Engineering and Science, Chia Nan University of Pharmacy and Science, 60, Sec. 1, Erren Rd., Rende Dist., Tainan City 71710, Taiwan; Indoor Air Quality Research and Service Center, Chia Nan University of Pharmacy and Science, 60, Sec. 1, Erren Rd., Rende Dist., Tainan City 71710, Taiwan.
Sci Total Environ. 2017 Apr 15;584-585:495-504. doi: 10.1016/j.scitotenv.2017.01.052. Epub 2017 Jan 25.
This study investigated allergenic terpenol compounds in incense powder and smoke. The powder of two Thai brands contained higher concentrations of terpenols up to 6.15 times higher than those of two Taiwanese brands. Consequently, Thai incense makers face a higher potential risk of contact dermatitis than Taiwanese incense makers do. d-Limonene was the primary terpenol compound in the powder of Thai B (64.0%) and Thai Y (31.5%), sold in Thailand. By contrast, anisyl alcohol was the primary terpenol compound in the powder of LST (40.3%) and SC (37.7%), sold in Taiwan. After the four brands of incense were ignited, their mean PM emission factor was 18.02±6.20mgg incense. The PM mass emission factors of the Taiwanese brands were far higher than those of the Thai brands, and so were the PM terpenol emission factors, showing that the smokes of the Taiwanese incense were potentially more allergenic than those of the Thai incense. Geraniol, the most allergenic terpenol compound, was 2.8%-10.7% of total terpenol compounds in the powder of the four brands, yet was the main contributor to PM, constituting 66.3%-83.5% of terpenol compounds in the smokes of the four brands. Furthermore, geraniol exhibited an IP ratio, defined as the incense/powder (IP) ratio of terpenol-related species, >1 in all four brands, and >5 in the Taiwanese brands, suggesting a greater health risk with the smoke from the Taiwanese incense. The IP ratios of other terpenol species were all <1, indicating decomposition through combustion. Additionally, the light/darkroom ratios of the terpenol species were >1, meaning that the generation of PM terpenol compounds was potentially enhanced by indoor lighting.
本研究调查了香粉和烟雾中的变应原萜醇化合物。两个泰国品牌的香粉中萜醇的浓度较高,最高可达两个台湾品牌的 6.15 倍。因此,与台湾的香制造商相比,泰国香制造商面临更高的接触性皮炎潜在风险。在泰国销售的泰国 B(64.0%)和泰国 Y(31.5%)香粉中的主要萜醇化合物为 d-柠檬烯。相比之下,在台湾销售的 LST(40.3%)和 SC(37.7%)香粉中的主要萜醇化合物为茴香醇。四个品牌的香点燃后,其平均 PM 排放因子为 18.02±6.20mgg 香。台湾品牌的 PM 质量排放因子远高于泰国品牌,PM 萜醇排放因子也是如此,表明台湾香的烟雾可能比泰国香更具变应原性。香叶醇是最具变应原性的萜醇化合物,占四个品牌香粉中总萜醇化合物的 2.8%-10.7%,但却是 PM 的主要贡献者,占四个品牌烟雾中萜醇化合物的 66.3%-83.5%。此外,香叶醇表现出 IP 比,定义为萜醇相关物质的香/粉(IP)比,在所有四个品牌中>1,在台湾品牌中>5,表明台湾香的烟雾健康风险更大。其他萜醇物质的 IP 比均<1,表明通过燃烧分解。此外,萜醇物质的明暗室比>1,这意味着室内照明可能会增强 PM 萜醇化合物的生成。