Furukawa Arata, Kuboki Satoshi, Shimizu Hiroaki, Ohtsuka Masayuki, Yoshitomi Hideyuki, Furukawa Katsunori, Takayashiki Tsukasa, Takano Shigetsugu, Suzuki Daisuke, Sakai Nozomu, Kagawa Shingo, Nojima Hiroyuki, Miyazaki Masaru
Dept. of General Surgery, Graduate School of Medicine, Chiba University.
Gan To Kagaku Ryoho. 2016 Nov;43(12):1969-1971.
A 79-year-old man was referred to our hospital because of sudden upper abdominal pain. Enhanced computed tomography revealed a huge multilocular cystic tumor with a thickened wall, which was connected with the main pancreatic duct of the pancreatic body. Abscess formation was seen inside the omental bursa; however, there were no signs of direct invasion of the cystic tumor into the stomach or transverse colon. Therefore, we performed emergency endoscopic naso-pancreatic drainage(ENPD)under the diagnosis of an intraperitoneal abscess caused by rupture of intraductal papillary mucinous carcinoma(IPMC). Four weeks later, distal pancreatectomy with omentectomy was performed to achieve curative resection of the ruptured IPMC. The postoperative course was uneventful and the patient was discharged on postoperative day 14. The pathological diagnosis was noninvasive IPMC. No signs of recurrence were seen until 12 months after surgery. Rupture of IPMC into the intraperitoneal space is rare; however, the prognosis is relatively poor because of the difficulty of curative resection. ENPD drainage before surgery is potentially useful for patients with ruptured IPMC to control local inflammation, which improves surgical curability.
一名79岁男性因突发上腹部疼痛被转诊至我院。增强计算机断层扫描显示一个巨大的多房囊性肿瘤,壁增厚,与胰体的主胰管相连。网膜囊内可见脓肿形成;然而,没有囊性肿瘤直接侵犯胃或横结肠的迹象。因此,在诊断为导管内乳头状黏液性癌(IPMC)破裂导致的腹腔脓肿后,我们进行了急诊内镜鼻胰管引流(ENPD)。四周后,行远端胰腺切除术加网膜切除术,以实现破裂的IPMC的根治性切除。术后过程顺利,患者于术后第14天出院。病理诊断为非侵袭性IPMC。术后12个月内未见复发迹象。IPMC破裂进入腹腔空间很少见;然而,由于根治性切除困难,预后相对较差。术前ENPD引流对破裂的IPMC患者控制局部炎症可能有用,这可提高手术治愈率。