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男性原发性乳腺癌

[Primary Breast Cancer in a Man].

作者信息

Watanabe Miho, Enomoto Katsuhisa, Sakurai Kenichi

机构信息

Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.

出版信息

Gan To Kagaku Ryoho. 2016 Nov;43(12):2249-2251.

PMID:28133285
Abstract

A 76-year-old man noticed a tumor under his right nipple. Mammography revealed an irregularly shaped nodule in the right breast. Ultrasonography showed a 20mm irregularly shaped nodule in the central area. MRI showed an 18mm irregularly shaped nodule in the central area with skin invasion. On core needle biopsy, the tumor was diagnosed as an invasive ductal carcinoma of the right breast. The patient underwent a mastectomy and axillary lymph node dissection. Histopathologically, the patient was diagnosed with invasive ductal carcinoma(scirrhous carcinoma). The tumor was positive for both ER and PgR, and the HER2 score was 1. The Ki-67 index was 20-30%. Male breast carcinoma accounts for approximately 1.0% of all breast carcinomas. The most common complaint is elastic, hard nodules with no pain. Postoperative therapy for male breast cancer is similar to that for female cancer. This patient underwent a mastectomy and lymph node dissection. After surgery, tamoxifen was administered as adjuvant therapy. There has been no evidence of recurrence for 4 months after the surgery.

摘要

一名76岁男性注意到其右乳头下有一个肿物。乳房X线摄影显示右乳有一个形状不规则的结节。超声检查显示中央区域有一个20毫米形状不规则的结节。磁共振成像显示中央区域有一个18毫米形状不规则且侵犯皮肤的结节。在粗针活检中,该肿瘤被诊断为右乳浸润性导管癌。患者接受了乳房切除术和腋窝淋巴结清扫术。组织病理学检查显示,患者被诊断为浸润性导管癌(硬癌)。肿瘤雌激素受体(ER)和孕激素受体(PgR)均呈阳性,人表皮生长因子受体2(HER2)评分是1分。Ki-67指数为20%-30%。男性乳腺癌约占所有乳腺癌的1.0%。最常见的症状是有弹性的硬结节,无疼痛。男性乳腺癌的术后治疗与女性乳腺癌相似。该患者接受了乳房切除术和淋巴结清扫术。术后给予他莫昔芬作为辅助治疗。术后4个月尚无复发迹象。

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