Variability in local action potential durations, dispersion of repolarization and wavelength restitution in aged wild-type and Scn5a mouse hearts modeling human Brugada syndrome.
作者信息
Tse Gary, Wong Sheung Ting, Tse Vivian, Yeo Jie Ming
机构信息
Department of Medicine and Therapeutics, Faculty of Medicine; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
Faculty of Medicine, Imperial College London, London, UK.
出版信息
J Geriatr Cardiol. 2016 Nov;13(11):930-931. doi: 10.11909/j.issn.1671-5411.2016.11.009.
Abstract
摘要
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Variability in local action potential durations, dispersion of repolarization and wavelength restitution in aged wild-type and Scn5a mouse hearts modeling human Brugada syndrome.老年野生型和模拟人类Brugada综合征的Scn5a小鼠心脏中局部动作电位持续时间的变异性、复极离散度和波长恢复情况。
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(Tpeak - Tend)/QRS and (Tpeak - Tend)/(QT × QRS): novel markers for predicting arrhythmic risk in the Brugada syndrome.（T峰 - T终末）/QRS及（T峰 - T终末）/（QT×QRS）：预测Brugada综合征心律失常风险的新型标志物。
Europace. 2017 Apr 1;19(4):696. doi: 10.1093/europace/euw194.
2
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Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse model.空间和时间异质性定位于杂合 Scn5a 小鼠模型的右心室流出道。
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