Mghirbi Fahmi, Ayadi Mouna, Karray Wafa, Yahyaoui Yosra, Meddeb Khedija, Mokrani Amina, Raies Henda, Chraeit Nesrine, Mezlini Amel
Department of Medical Oncology, Salah Azaiez Institute, Tunis, Tunisia.
Transl Gastroenterol Hepatol. 2016 Oct 20;1:78. doi: 10.21037/tgh.2016.09.07. eCollection 2016.
Gallbladder cancer is the most common malignant tumor of the biliary tract. The majority of cases are adenocarcinoma (AC). Pure squamous cell carcinoma (SCC) of gallbladder accounts only 3% of the malignant neoplasm of this organ. Many patients are at advanced stage when diagnosed and have bad therapeutic efficacy. At present, radical surgery is the only chance to gain long-term survival for patients with early-stage gallbladder cancers. Recent reports have shown a benefit of adjuvant chemoradiation in this type of tumor. At present, no therapy is defined for unresectable cancer of the gallbladder, especially for SCC.
胆囊癌是最常见的胆道恶性肿瘤。大多数病例为腺癌(AC)。胆囊纯鳞状细胞癌(SCC)仅占该器官恶性肿瘤的3%。许多患者在确诊时已处于晚期,治疗效果不佳。目前,根治性手术是早期胆囊癌患者获得长期生存的唯一机会。最近的报告显示辅助放化疗对这类肿瘤有益。目前,对于无法切除的胆囊癌,尤其是鳞状细胞癌,尚无明确的治疗方法。