Domnişoru L, Chiriac E
Rev Med Chir Soc Med Nat Iasi. 1989 Apr-Jun;93(2):389-90.
The authors investigate 20 cases of acute carbon tetrachloride (CCl4) poisoning representing 50% of all acute poisonings with organo-chlorate solvents admitted during a 5-year interval to Galaţi District Hospital. All our CCl4 acute poisoning cases were accidental, mild and moderate in form, and prevailed in man (80%). Depending on the ingested (more seldom) or inhaled amounts, CCl4 induces neurological and or digestive disturbances, parenchymatous involvements, prevalently hepatic (misdiagnosis of acute viral hepatitis and leptospirosis) or mixed, hepatorenal. Characteristic to the mixed form is the staged evolution of the clinico-biological manifestations, acute toxic hepatitis in the first week and acute toxic tubulo-interstitial nephropathy in the second one, both requiring proper management. Five selected cases are presented.
作者对20例急性四氯化碳（CCl₄）中毒病例进行了调查，这些病例占加拉茨地区医院5年间收治的所有有机氯溶剂急性中毒病例的50%。我们所有的急性CCl₄中毒病例均为意外事故，中毒形式为轻度和中度，男性患者居多（80%）。根据摄入（较少见）或吸入的量不同，CCl₄会引发神经和/或消化系统紊乱、实质器官受累，主要是肝脏受累（误诊为急性病毒性肝炎和钩端螺旋体病）或混合性肝肾受累。混合形式的特点是临床生物学表现呈阶段性演变，第一周为急性中毒性肝炎，第二周为急性中毒性肾小管间质性肾病，两者都需要妥善处理。文中展示了5例经挑选的病例。
