Pinter Jule, Hanson Camilla S, Chapman Jeremy R, Wong Germaine, Craig Jonathan C, Schell Jane O, Tong Allison
Sydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.
Clin J Am Soc Nephrol. 2017 Mar 7;12(3):443-453. doi: 10.2215/CJN.05890616. Epub 2017 Jan 31.
Older kidney transplant recipients are susceptible to cognitive impairment, frailty, comorbidities, immunosuppression-related complications, and chronic graft failure, however, there has been limited focus on their concerns and expectations related to transplantation. This study aims to describe the perspectives of older kidney transplant recipients about their experience of kidney transplantation, self-management, and treatment goals to inform strategies and interventions that address their specific needs.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Face-to-face semistructured interviews were conducted with 30 kidney transplant recipients aged 65-80 years from five renal units in Australia. Transcripts were analyzed thematically.
Six themes were identified: restoring vitality of youth (with subthemes of revived mindset for resilience, embracing enjoyment in life, drive for self-actualization); persisting through prolonged recovery (yielding to aging, accepting functional limitations, pushing the limit, enduring treatment responsibilities); imposing sicknesses (combatting devastating comorbidities, painful restrictions, emerging disillusionment, anxieties about accumulating side effects, consuming treatment burden); prioritizing graft survival (privileged with a miracle, negotiating risks for longevity, enacting a moral duty, preserving the last opportunity); confronting health deterioration (vulnerability and helplessness, narrowing focus to immediate concerns, uncertainty of survival); and value of existence (purpose through autonomy, refusing the burden of futile treatment, staying alive by all means).
Older kidney transplant recipients felt able to enjoy life and strived to live at their newly re-established potential and capability, which motivated them to protect their graft. However, some felt constrained by slow recuperation and overwhelmed by unexpected comorbidities, medication-related side effects, and health decline. Our findings suggest the need to prepare and support older recipients for self-management responsibilities, clarify their expectations of post-transplant risks and outcomes, and provide assistance through prolonged recovery after kidney transplantation.
老年肾移植受者易患认知障碍、身体虚弱、合并症、免疫抑制相关并发症以及慢性移植失败,然而,对于他们与移植相关的担忧和期望关注有限。本研究旨在描述老年肾移植受者对肾移植经历、自我管理及治疗目标的看法,以为满足其特定需求的策略和干预措施提供信息。
设计、地点、参与者及测量方法:对来自澳大利亚五个肾脏科室的30名年龄在65至80岁之间的肾移植受者进行了面对面的半结构化访谈。对访谈记录进行了主题分析。
确定了六个主题:恢复青春活力(包括恢复适应力的心态、享受生活、追求自我实现等子主题);在漫长康复过程中坚持(屈服于衰老、接受功能限制、挑战极限、承担治疗责任);忍受疾病(对抗严重合并症、痛苦的限制、出现的幻灭感、对副作用积累的焦虑、治疗负担);优先考虑移植存活(有幸获得奇迹、权衡长寿风险、履行道德责任、保留最后机会);面对健康恶化(脆弱与无助、将关注点缩小到眼前问题、生存的不确定性);以及存在的价值(通过自主获得意义、拒绝无效治疗的负担、不惜一切代价活着)。
老年肾移植受者感到能够享受生活,并努力在新确立的潜力和能力水平上生活,这促使他们保护自己的移植肾。然而,一些人感到康复缓慢受到限制,并且被意外的合并症、药物相关副作用和健康衰退压得喘不过气来。我们的研究结果表明,需要为老年受者做好准备并支持他们承担自我管理责任,明确他们对移植后风险和结果的期望,并在肾移植后漫长的康复过程中提供帮助。