99mTc-HYNIC-TOC闪烁扫描术中胰腺生长抑素受体的生理表达
Physiological expression of pancreatic somatostatin receptors in 99mTc-HYNIC-TOC scintigraphy.
作者信息
de la Cueva L, Lloro P, Sangrós M J, López Vélez L, Navarro P, Sarria L, Álvarez S, Abós D
机构信息
Nuclear Medicine Department, University Hospital Miguel Servet, Paseo Isabel la Católica 1-3, 50009, Zaragoza, Spain.
Clínica las Américas, Medellín, Colombia.
出版信息
Clin Transl Oncol. 2017 Jul;19(7):915-920. doi: 10.1007/s12094-017-1616-3. Epub 2017 Jan 31.
PURPOSE
To describe the frequency of head and/or pancreas uncinate process uptake of 99mTc-HYNIC-TOC, to study its nature, and analyze its diagnostic value.
MATERIALS AND METHODS
Retrospective evaluation of 47 consecutive 99mTc-HYNIC-TOC examinations was conducted. Head and/or pancreas uncinate process uptake was considered to be physiological in patients with normal CT at the same episode and in follow-up. It was analyzed if age or diabetes mellitus was justifying the existence or not of uptake.
RESULTS
32.5% patients showed uptake; 73% of them were mild. 84.6% patients with uptake have no pathology and 4% had neuroendocrine pancreatic disease at CT. Neither the age nor the diabetes mellitus established differences in patients without lesion.
CONCLUSIONS
Near one-third of patients show physiological uptake by head and/or pancreas uncinate process at 99mTc-HYNIC-TOC scintigraphy. It seems that neither the diabetes nor the ages are factors that determine this physiological uptake.
目的
描述99mTc-HYNIC-TOC在头部和/或胰腺钩突摄取的频率，研究其性质，并分析其诊断价值。
材料与方法
对连续47例99mTc-HYNIC-TOC检查进行回顾性评估。在同一时期及随访中，CT正常的患者中，头部和/或胰腺钩突摄取被认为是生理性的。分析年龄或糖尿病是否是摄取存在的合理原因。
结果
32.5%的患者出现摄取；其中73%为轻度摄取。84.6%有摄取的患者无病变，4%在CT检查时有胰腺神经内分泌疾病。在无病变的患者中，年龄和糖尿病均未显示出差异。
结论
在99mTc-HYNIC-TOC闪烁扫描中，近三分之一的患者头部和/或胰腺钩突出现生理性摄取。糖尿病和年龄似乎都不是决定这种生理性摄取的因素。
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